Plamed Green Science Group

Beta Arbutin is often referred to as just Arbutin. It is can be naturally extracted from plants such as bearberry and synthesized by chemical method. Synthesized Beta-Arbutin is currently one of the most widely used hypopigmenting agents in cosmetics, while plant-derived drugs containing Beta Arbutin were initially used for the treatment of urinary tract infections, cystitis, kidney stones, and as diuretics in the medical field.

Aloe Vera powder Extract is a water-soluble natural cosmetic raw material extracted from aloe vera leaves. It is rich in vitamin B2, vitamin B6, vitamin B12, 8 kinds of amino acids which are necessary for human skin, and some minerals. Aloe extract shows a variety of biological activities, it’s an important cosmetic additive. It has a good effect on rejuvenation and anti-aging for its promotion of fibrin growth, inhibition of elastin, and the elimination of free radicals by the synthesis of collagen. It promotes the synthesis of cholesterol, helps to change the composition of sebum, reduces facial glossy and softens skin. Also it has antibacterial, anti-inflammatory and moisturizing effects.

Paeoniflorin 70% is a derivative of monoterpene, mainly derived from dried root of plant white peony (accounting for 3% of white peony). It is a main effective ingredient of total glucosides of paeonia (TPG). Plamed develops two specifications: 70% Paeoniflorin and 98% Paeoniflorin. Both of them are natural cosmetic raw materials. Paeoniflorin is off-white fine powder. It’s lightly soluble in water, and soluble in ethanol and acetone. Paeoniflorin is hydrolyzed and polymerized in a dilute alkali solution; and it will slowly degrade in a slightly acidic aqueous solution. Emulsions made of non-ionic surfactants can slow down this process. Paeoniflorin has great development prospect in market of cosmetic raw material, because of its various biological activities. Paeoniflorin is characterized by scavenging free radicals and resisting oxidative damage. It inhibits NF-kB cells and improves immune property of skin cells. It greatly exerts anti-inflammatory effect. Thus Paeoniflorin can be used in combination with other effective ingredients to treat skin sores, acne, pimple, sunburn and so on. Paeoniflorin inhibits melanin production due to its anti-oxidation and anti-inflammatory activities. It reduces skin pigmentation; and it has a non-dose-dependent whitening effect. In addition, Paeoniflorin can prevent and improve intrinsic skin aging and UV-induced skin aging. It has an anti-wrinkle effect.

Sodium Ascorbyl Phosphate (SAP) is a stable vitamin C derivative. It is processed from vitamin C as a raw material. After entering human body, it rapidly transforms into VC through enzymolysis. Thereby, SAP plays its unique physiological and biochemical functions. Sodium Ascorbyl Phosphate is white or pale yellow powder. It is soluble in water, propylene glycol and glycerin; but it’s almost insoluble in ethanol. Sodium Ascorbyl Phosphate is a water-soluble cosmetic whitening additive. After transdermal absorption, it can effectively resist ultraviolet damage, and capture free radicals. Also it can promote collagen production. It has anti-oxidation and anti-aging effect. Moreover, SAP can effectively prevent pigmentation; it helps to eliminate skin spots, such as freckles and age spots. In addition, Sodium Ascorbyl Phosphate has a therapeutic effect on facial acne and pimple.

Ascorbic Acid 2-Glucoside（AA2G）, also named Ascorbyl Glucoside, is one of vitamin C derivatives. It is synthesized by biological transformation and uses glycosyl transferase as raw material. It retains all biological activities of vitamin C. It is more stable than vitamin C, and is the most stable derivative of vitamin C. AA2G is one of the whitening additives recognized by the Department of Health. It inhibits the activity of tyrosinase, and reduces the formation of melanin. Furthermore, it restores melanin, alleviates the melanin that has formed, and reduces the pigmentation. Thereby it can exert skin whitening and brightening effect. Ascorbic Acid 2-Glucoside can also promote the synthesis of collagen. It relieves skin wrinkles and rough dry skin, so that the skin looks plump and bright. As a highly effective whitening agent, Ascorbic Acid 2-Glucoside has long been recognized in the cosmetics market. Many well-known brands at home and abroad (such as Lancome, SK2, Kiehl’s, Clinique, etc.) have added it into cosmetics to better play its whitening effect.

Glabridin is a kind of flavonoids, extracted from the dry rhizomes of Glycyrrhiza glabra. It is known as “whitening gold” because of its powerful whitening effect. Glabridin can effectively inhibit tyrosinase activity, thereby inhibiting the production of melanin. It is a safe, mild as well as effective whitening active ingredient. Experimental data show that the whitening effect of Glabridin is 232 times that of vitamin C, 16 times that of hydroquinone, and 1164 times that of arbutin. As the top three whitening ingredients and ranked 11th in the popularity of functional ingredients, Glabridin has always been favored by consumers. Data show that the popularity of Glabridin is increasing year by year. As a popular and effective raw material, its value is discounted because of its high cost. As a result, Plamed develops PCR water-soluble Glabridin. On the basis of more convenient application, it significantly improves the bioavailability of the product. Experimental data show that the bioavailability of PCR water-soluble Glabridin is 3.1 times that of ordinary Glabridin, which can help customers greatly reduce the cost of adding Glabridin.

Tetrahydrocurcumin (THC) is the most active and principal intestinal metabolite of curcumin. It comes from hydrogenated curcumin that is from turmeric root. THC has a great effect of skin-whitening. Also it can prevent the production of free radicals, and eliminate free radicals that have formed. So, it has obvious antioxidant effects, such as anti-aging, repairing skin, diluting pigment, removing freckle, and so on. Nowadays, THC has been widely used as a natural whitening agent, and it enjoys vast potentials in cosmetics industries.

Astaxanthin is a natural carotenoid, widely found in aquatic animals, bird feathers and micro algae. It has strong antioxidant activity. But because of its poor water solubility and stability, astaxanthin is very easy to be oxidized and decomposed when encountering light, heat, oxygen, etc., which reduces its bioavailability. Plamed develops astaxanthin water emulsion by nano-emulsification technology that overcomes the above shortcomings. Astaxanthin water emulsion is easily absorbed by skin, and still has a strong anti-oxidation property. Transdermal tests have shown that astaxanthin water emulsion can change the tight structure of skin stratum corneum. It can promote the penetration and absorption of astaxanthin, and increase the retention of astaxanthin in skin. Cytotoxicity and skin irritation experiments proved that astaxanthin water emulsion has better safety at a certain concentration, and there is no obvious irritation to human skin. As the strongest antioxidant agent in nature, astaxanthin’s antioxidant activity is 1000 times that of vitamin C. Astaxanthin can effectively protect the skin from ultraviolet (UVA, UVB) damage. Its super strong ability to eliminate free radicals can prevent skin cells from being damaged by free radicals, and reduce wrinkles and fine lines. As a super anti-oxidant agent for cosmetic, astaxanthin is widely used in various cosmetics such as cream, serum, eye cream, facial mask and lotion.

Nicotinamide & Niacinamide is a vitamin B form. It can be also called Vitamin B3. It is a significant niacin derivative, mainly occurring in many organisms. Nicotinamide & Niacinamide can produce coenzyme Ⅰ and Ⅱ when it reacts with ribose, adenine and phosphoric acid. Also it boosts the synthesis of DNA, fats and proteins and improves the energy metabolism of cells. So it can greatly prevent melanin deposition, and reduce discoloration. It has an effective whitening function. Nowadays, as a natural cosmetics ingredient, it is widely applied in skin and hair care products. Plamed Nicotinamide is divided into medical grade and cosmetics grade.