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Plamed Green Science Group Ergothioneine (EGT)

Plamed Green Science Group Ergothioneine (EGT) is a natural amino acid with potent antioxidant activity. It is a water-soluble cosmetic raw material; it has good light and heat stability, and is not easily decomposed by oxidation. Therefore, ergothioneine is easy to be compatible with other active materials in cosmetics formulas. Moreover, ergothioneine is non-toxic in epidermal cells, so it will not produce any irritation when used topically with safety and effectiveness. Ergothioneine is a natural ultraviolet protective agent, which can block the damage of ultraviolet rays to the skin, and play a role in sun protection. It can also repair damaged collagen and elastic fibers. Ergothioneine can also effectively remove high-concentration free radicals in the human body, whiten the skin, and delay skin aging. Studies have shown that when ergothioneine is used together with other antioxidants, it has a good synergistic whitening and anti-aging effect.

INCI Name: Ergothioneine

Functions: Antioxidant

Ingredient Origin: Fermentation

Labeling Claims: Clean at Sephora, Credo Clean Standard, Natural, Ulta Beauty's Conscious Beauty

Benefit Claims: Antioxidant Properties, Skin Whitening

Certifications & Compliance: CFDA Compliant (China)

    Knowde Enhanced TDS

    Identification & Functionality

    Chemical Family
    INCI Name
    Ingredient Origin
    Cosmetic Ingredients Functions
    Molecular Formula
    C9H15N3O2S
    CAS No.
    497-30-3
    EC No.
    207-843-5
    Molecular Structure

    Plamed Green Science Group Ergothioneine (EGT) - Molecular Structure

    Features & Benefits

    Benefits
    • Anti-oxidation - Ergothioneine has anti-oxidation ability. Under the condition of continuous ultraviolet irradiation for 18 hours, 70% of the cells are still reductive, because of ergothioneine’s exist. Ergothioneine inhibits lipid per-oxidation, prevents the production of active oxides, and reduces the apoptosis of irradiated cells. Thereby it can prevent skin aging and effectively improve fine lines and wrinkles. A study use emulsion containing 2.0% EGT once a day for 4 weeks. As a result, the participant’s skin wrinkles reduce significantly, and the skin becomes more bright. Show as following picture.
    • Sun Protection - In the ultraviolet absorption range, ergothioneine has an absorption wavelength similar to that of DNA, with a molar extinction coefficient of 1.4*104 M-1 cm-1, λmax257. It can decrease the formation of reactive oxygen species and protect skin cells from UV-radiation damage. Therefore, ergothioneine can be used as a physiological filter of ultraviolet rays; it can avoid the damage caused by ultraviolet rays to the skin. In a word,  ergothioneine is a very effective sunscreen ingredient.

    Applications & Uses

    Source

    In 1909, ergothioneine was first discovered in Claviceps purpurea. Later, it was also found in animals’ organ. At present, there are three main sources of ergothioneine. They are chemical synthesis, biosynthesis, and animal and plant extraction. Microorganisms such as spirulina, ascomycetes, mycobacteria, and basidiomycetes can bio-synthesize ergothioneine. At the same time, ergothioine is also present in the fruiting bodies of edible fungi, such as bisporus, oyster mushroom. Nowadays, biosynthesis is mostly used for large-scale production of ergothioneine. Ergothioneine produced by this method has high purity and few impurities.

    Properties

    Physical Form
    Physical Properties
    ValueUnitsTest Method / Conditions
    Moisturemax. 2.0%-
    Residue on ignitionmax. 1.0%-
    Particle size (NTL pass 60 mesh)98%-
    Typical Properties
    ValueUnitsTest Method / Conditions
    Molecular Weight229.3g/mol-
    Specification99%-
    Assay (on dry basis, L- Ergothioneine)min. 98%-
    AppearanceOff-white to white crystalline powder--
    Odor and tasteStrong and characteristic--
    Microbiological Values
    ValueUnitsTest Method / Conditions
    Total plate countmax. 1000cfu/g-
    Yeast & moldmax. 100cfu/g-
    ColiformNegative--
    SalmonellaNegative/10g
    Staphylococcus aureusNegative--
    Heavy Metals
    ValueUnitsTest Method / Conditions
    Total heavy metals (as Pb)max. 10ppm-
    Pbmax. 1ppm-
    Asmax. 1ppm-
    Hgmax. 0.1ppm-
    Cdmax. 1ppm-

    Regulatory & Compliance

    Certifications & Compliance

    Safety & Health

    Safety
    • CTFAhas recognized ERGOTHIONEINE as a raw material for cosmetics;
    • The International Catalog of Chinese Cosmetic Raw Materials Standardsin 2010 issued by ERGOTHIONEINE.
    • On the Announcement of Name List of Cosmetics Raw Materialpublished by CFDA in 2021 both include ERGOTHIONEINE. There are no reports indicating that ERGOTHIONEINE is unsafe for external use.

    Packaging & Availability

    Packaging Type
    Packaging
    • 10g/bag, 100g/bag, 1kg/bag.
    • Minimal Package - 10G
    • Minimal Order Quantity - 10G

    Storage & Handling

    Storage

    Stored in a cool dry place and away from direct sunlight and oxidizing agents.