company tower banner
Shin-Etsu Pharma, Nutra and Food Company Logo

METOLOSE® SB-4

1 of 32 products in this brand
METOLOSE® consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) . METOLOSE SB-4 is an excellent sugar coating binder for solid dosage forms.

Chemical Name: Hydroxypropyl Methylcellulose

Functions: Binder, Thickener, Viscosity Modifier

Labeling Claims: Non-Hazardous

Certifications & Compliance: European Pharmacopeia (Ph. Eur.), Japan Pharmacopeia (JP), United States Pharmacopeia (USP)

    Knowde Enhanced TDS

    Identification & Functionality

    Pharma & Nutraceuticals Functions
    CAS No.
    9004-65-3
    EC No.
    618-389-6

    Features & Benefits

    Labeling Claims
    Features
    • Non ionic and water soluble polymer with various viscosity.
    • Applicable as film strips and dispersant of liquid formulation.
    • SM-4 is recommendable for pellet coating as it is less sticky. The thermal gelling helps to prevent agglomerations during the coating process even at the higher spray speed.

    Applications & Uses

    Properties

    Appearance
    White or slightly off - white powder, fibrous powder or granules.
    Typical Properties
    ValueUnitsTest Method / Conditions
    Hydroxypropoxy Content4.0 - 7.5%
    Methoxy Content27.0 - 30.0%
    True Density1.26 - 1.31g/ml
    Bulk Density0.20 - 0.45g/ml
    Tapped Density0.35 - 0.65g/ml
    Degradation Temperature280 - 300°C
    HygroscopicityDepends on substitution type
    Dust Explosion100bar.m/s
    Viscosity (2 w/w % aqueous solution at 20°C)3.2 - 4.8mPa.s
    Thermal Properties
    ValueUnitsTest Method / Conditions
    Self Ignition Temperatureapprox. 360°C
    Typical Analysis
    ValueUnitsTest Method / Conditions
    Angle of Repose35 - 50°

    Regulatory & Compliance

    Regulatory Information
    • This material is not hazardous as defined by 49CFR 172.101 by the U.S. department of transportation.
    • This substance is not classified as hazardous according to Regulation (EC) No 1272/2008 (CLP).
    • This substance is listed in current US Pharmacopeia, European Pharmacopeia and Japanese Pharmacopeia.

    Technical Details & Test Data

    Surface Activity

    METOLOSE® can be considered a non-ionic surfactant, as it has both hydrophilic and hydrophobic groups in the molecule. Due to such characteristics, it functions as a superior protective colloid, being effective for the stabilization of emulsions, suspensions, and foams.

    METOLOSE® SB-4 - Surface Activity

    Packaging & Availability

    Packaging Information

    Packaging material: Double-layered polyethylene bag in fiber drum.

    Storage & Handling

    Storage Information
    • Keep dry. Store away from excess heat and sunlight.
    • Store in sealed containers.