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Amitose™ GCA is a versatile cosmetic active designed for creams. Its remarkable benefits include being non-sticky, moisturizing, and offering collagen protection and boosting properties. This innovative ingredient also prevents melanin production, ensuring superior skin feel and improved stability. With its antioxidant properties, courtesy of its chemical family of ascorbates, Amitose™ GCA is a preservative-free and cold processable solution. Ideal for skin care in the realm of beauty and personal care.

INCI Name: Cetyl 2-Glyceryl Ascorbate, Pentylene Glycol

Functions: Antioxidant

Labeling Claims: Cold Processable, Preservative-free

Benefit Claims: Age & Dark Spot Reduction, Collagen Boosting, Collagen Protection, Improved Stability, Moisturizing, Non-Sticky, Superior Skin Feel

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Knowde Enhanced TDS

Identification & Functionality

Chemical Family
Cosmetic Ingredients Functions

Features & Benefits

Applications & Uses

Application Format

Properties

Composition
ValueUnitsTest Method / Conditions
Pentylene Glycol68%
Cetyl 2-Glyceryl Ascorbate32%
Compatibility with Various Oils in Emulsification
Oil Type   Compatibility
Ester oils Caprylic/Capric Triglyceride Excellent
Cetyl Ethylhexanoate Very good
Hydrocarbon oils Squalane Very good
Triglycerides Olea Europaea (Olive) Fruit Oil Very good
Silicone oils Dimethicone Good

 

Technical Details & Test Data

iVC Emulsification Procedure

Sensory Evaluation

[Experimental method]
10 panelists evaluated the sensory texture of skin and gave 2 point to a better evaluation item, or 1 point to each items when they feel same sensory texture. The graph shows the sum of total points.

Temporal Stability

After 2 Months at 50°C

*2 A cream using PEG-60 hydrogenated castor oil (0.20%) instead of Amitose GCA (Cetyl 2-Glycery Ascorbate: 0.20%) in the iVC emulsifying cream formulation, containing same amount of polyhydric alcohol.

Physiological Effects

Enhancement of Collagen Production

[Experimental method]

Normal human dermal fibroblasts were cultured for 1 day, the medium was replaced with medium containing sample, and the culture was continued. At 2 days after the exchange of medium, part of culture was taken for determining the collagen content by competitive enzymelinked immunosorbent assay (ELISA).

Inhibition of Melanin Production

[Experimental method]

Melanocytes were cultured for 1 day, the medium was added to sample and melanin production enhancing agent (theophyline), and the culture was continued. At 3 days after the medium exchange, the medium was removed, and the produced amounts of melanin in the cell were determined.