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Japanese time-tested manufacturer of innovative cosmetic ingredients, Seiwa Kasei offers high-performance products based on peptides and/or amino acids and formulations with unique marketing claims and relevant data. In addition to the core products "Promois" - variants of hydrolyzed proteins and their derivatives from natural resources -, many functional ingredients are developed with our technology, such as "Silasoma" - encapsulated UV-filters for sensitive skin and baby -, "Protesil" - multi-functional hybrid polymers with silky texture, hair color protection -, "Amitose" - glycerin derivatives with arginine or ascorbic acid with moisturizing effect and whitening effect - and "Vegetamide" -pseudo-F layer of hair cuticle with selective repair.

Amitose™ 3GA

Amitose™ DGA

Promois™ WJ-SP

Vegetamide™ 18MEA-NJ

Amitose™ R-PD

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Promois is the trademark for peptides and their derivatives obtained through hydrolysis of natural proteins. They are raw materials for cosmetics with an excellent conditioning effect that moisturizes, protects, and repairs skin and hair, and are gentle to human and friendly to the environment. It has different functions in every origin and derivative.

Promois

Vegetamide is a plant-derived hair conditioning ingredient that has a similar structure to F-Layer (main component: 18-MEA), which is the barrier structure of hair cuticles. The hair surface, which is stripped of its F-layer due to hair damage, can be restored to a healthy state by concentrated repair with the similarly structured Vegetamide.

Vegetamide

Silasoma is water dispersion of microcapsules, encapsulated UV absorbers. Concern related to the safety of UV absorbers and their heavy oily feeling on the skin lead us to encapsulate the raw material, we have developed with our own original patented technology, resulting in the successful development of Silasoma, an ingredient that protects against UV rays and is gentle on the skin. In addition to being very safe, Silasoma also has a useful feature in that it provides a soft and light after-feel that is devoid of stickiness, and that it allows the formulation of surfactant-free sun protection products. It can also be incorporated into hair care products.

Silasoma

Amitose VC series is developed by derivatization of the fragile vitamin C with glycerin in order to improve the stability against oxidation, and so now it is possible to be formulated it into cosmetics with confidence. Because Amitose VC series has an inhibitory effect on melanin production and a moisturizing effect, it is suitable for being applied to aging-care cosmetics. There are some products having additional unique effects such as antioxidant effect, enhancing effect on collagen production, oil-in-water emulsifying ability and antibacterial effect. It can be formulated into skin toner, gel serum, and emulsion such as skin cream, thus allowing it to be used in a wide range of formulations and dosage forms.

Amitose

PhytoCuticle is a plant-derived hair conditioning ingredient that has a similar structure to F-Layer (main component: 18-MEA), which is the barrier structure of hair cuticles. The hair surface, which is stripped of its F-layer due to hair damage, can be restored to a healthy state by concentrated repair with the similarly structured PhytoCuticle.


PhytoCuticle

The Protesil series are hybrid polymers that combine three different types of substances, namely peptides, an alkyl group and silicone, all of which possess different properties. Since the peptide portion exhibits a hydrophilic property, while the alkyl group shows affinity to hydrocarbons and silicone demonstrates affinity for silicone oils, Protesil is highly compatible with various raw materials incorporated into cosmetics formulations. In addition, we are developing product counts for the Protesil series possessing different characteristics, depending on the balance of the three components in the polymer structure.

Protesil

BLACK PEARL Extract™ is an extract obtained from the black mother of pearl shells in Tahiti. It is an upcycling ingredient developed from Pinctada margaritifera (the black mother of pearl shells) cultured by the French Tahitian sea. Both “Luxury” and “Sustainable” can be appealed.

BLACK PEARL Extract

Amitose R is a premium moisturizer produced by binding moisturizer “glycerin” to amino acid “arginine” using our own original technology. The excellent absorption property derived from the arginine structure and high moisturizing effect derived from the glycerin structure offers long-lasting moistness. Amitose R is stable and has various effects, so it can be applied to wide range of cosmetic formulations from hair care to skin care products.

Aminoreact

Vistanol is a series of ester oils that are highly stable against oxidation. It barely has any color or smell, and is suitable for incorporation into skin care and make-up formulations.

Vistanol

Amitose™ HGA, "Lightening vitamin C", is a novel stable vitamin C derivative produced by binding Vitamin C (ascrobic acid), glycerin and an alkyl group together using SEIWA KASEI's original technology. It provides excellent skin moisture but particularly excels at skin lightening. In fact, Amitose™ HGA skin lightening mechanism is the world first of its kind. First, it inhibits melanin synthesis more effectively than most ascorbic acid derivatives. Secondly, Amitose™ HGA inhibits and reverses melanin transport. Lastly, melanin is degraded by autophagy which won the 2016 Nobel Prize. Those mechanism leads to consequently supress dark spots, a truly unique mechanism in Vitamin C derivatives. Amitose™ HGA can be used in a large variety of formulae : skin toners, transparent gel-serums and emulsions such as creams. This product is preservative free water-soluble ingredient. It is developed and manufactured in Japan by SEIWA KASEI.

Amitose™ HGA

Promois™ WK-HSIGF is a silylated derivative type of hydrolyzed keratin. It protects and repairs hair, and improves its texture by a heat enhancing effect that results in the formation of a film on the hair in response to heat from hair dryers or hair ironing. Keratin is one of the structural proteins composing the stratum corneum, hair, and nails. It makes up 80% of human hair. About its amino acid composition, it must be noted that keratin has plenty of cystine, the amino acid that forms a bond between the helix of the protein and thus provides physical resistance to the hair structure as well as moisture. This is why it is important to supply keratin regularly through hair care products. Promois™ series is a range of peptides and derivatives obtained through hydrolysis of natural proteins. There are also products with different preservatives. It is developed and manufactured in Japan by SEIWA KASEI.

Promois™ WK-HSIGF

Vegetamide™ 18MEA-R, "Plant-derived Liquid Cuticle" has aliphatic cationic compounds of rice peptides with hair conditioning efficacy. The F-Layer, which main component is called 18-MEA, is the barrier structure of hair cuticles, but it can be stripped off due to hair damage. Because Vegetamide™'s structure mimics the structure of the F-Layer, it can repair and restore the hair cuticles to a healthy state and improve its texture. This product is preservative free. It is developed and manufactured in Japan by SEIWA KASEI.

Vegetamide™ 18MEA-R

Promois™ WG-SP is powder hydrolyzed wheat protein with conditioning efficacy. Wheat protein is rich in acidic amino acids and particuarly in glutaminc acid which provides moisturizing effect. It also has a slight amount of cystine, the amino acid tht brings strength to the hair. Lastly,compared with other plant proteins, wheat proteins tend to have a lighter texture. Promois™ WG-SP is an organic ingredient certified ECOCERT and COSMOS. This product is preservative free powder type. Promois™ series is a range of peptides and derivatives obtained through hydrolysis of natural proteins. It is developed and manufactured in Japan by SEIWA KASEI.

Promois™ WG-SP

Solublekeratin SKSP is a water-soluble keratin polymer of natural wool origin. Keratin is the one of main components of stratum corneum which protects skin against external stimulations (UV, Chemical) and keeps water in epidermis. Soluble Keratin SKSP improves barrier function and provides smoothness as well. It is also suitable for nail care formulations because its main component is keratin. This product is preservative free powder type. It is developed and manufactured in Japan by SEIWA KASEI.

Solublekeratin SKSP

Promois™ SILK-1000F is hydrolyzed silk protein with hair conditioning efficacy. Silk protein is formed of two proteins: fibroin and sericin. Fibroin has a unique amino acid composition. It is rich in glycine, alanine and serine which have small molecular weight and simple chemical structure. This composition is known to form a sheet structure to which is associated the comfortable touch of silk. Many of the amino acids of sericin have hydroxyl groups which provides uncomparable moisturizing effect. Promois™ series is a range of peptides and derivatives obtained through hydrolysis of natural proteins. There are also products with different preservatives. It is developed and manufactured in Japan by SEIWA KASEI.

Promois™ SILK-1000F

Protesil™ LH is a novel hybrid polymer created from the fusion of silk peptides and silicone. It can be used as a multi-functional hair conditioning ingredient. It has excellent adsorption to hair and forms a thin film on the surface of hair, which is glossy, long-lasting, and water-resistant. This has various effects such as repairing, moisturizing, color-protection, shine and anti-static effect. This product is preservative free. It is developed and manufactured in Japan by SEIWA KASEI.

Protesil™ LH

Amitose™ DGA, "Rich-Moisturizing vitamin C", is a novel stable vitamin C derivative produced by binding Vitamin C (ascorbic acid) and two glyceryl groups using SEIWA KASEI's original technology. In addition to inhibiting melanin production it provides ultra moisture to the skin as it strenghtens the cornified cell envelope in the stratum corneum. As a non-ionic ingredient it can be used easily in gel and emuslion formulae such as creams but it is also notably recommended for transparent gel-serums, Vitamin C-rich serum and skin toners. This product is preservative free water-soluble ingredient. It is developed and manufactured in Japan by SEIWA KASEI.

Vegetamide™ 18MEA-NJS, "Plant-derived Liquid Cuticle" has aliphatic cationic compounds of pea peptides with hair conditioning efficacy. The F-Layer, which main component is called 18-MEA, is the barrier structure of hair cuticles, but it can be stripped off due to hair damage. Because Vegetamide™'s structure mimics the structure of the F-Layer, it can repair and restore the hair cuticles to a healthy state and improve its texture. This product is the preservative free. It is developed and manufactured in Japan by SEIWA KASEI.

Vegetamide™ 18MEA-NJS

Seiwa Kasei

Japanese time-tested manufacturer of innovative cosmetic ingredients, Seiwa Kasei offers high-performance products based on peptides and/or amino acids and formulations with unique marketing claims an

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Promois™ EF-118(IS) is an acylated derivative of hydrolyzed silk protein. This is oil-soluble and it can be formulated into waterless formulae such as hair oil. Silk protein is formed of two proteins: fibroin and sericin. Fibroin has a unique amino acid composition. It is rich in glycine, alanine and serine which have small molecular weight and simple chemical structure. This composition is known to form a sheet structure to which is associated the comfortable touch of silk. The amino acids of sericin have many hydroxyl groups which provides uncomparable moisturizing effect. This product is preservative free. Promois™ series is a range of peptides and derivatives obtained through hydrolysis of natural proteins. It is developed and manufactured in Japan by SEIWA KASEI.

Promois™ EF-118(IS)

Promois™ EF-118(IS) is an acylated derivative of hydrolyzed silk protein. This is oil-soluble and it can be formulated into waterless formulae such as hair oil. Silk protein is formed of two proteins:

Promois EF-118(IS) - Seiwa Kasei - Isostearic Acid - Conditioner

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	Value	Units	Test Method / Conditions
Active Content	3	%	—
Molecular Weight	500	—	—

Promois™ EF-118(IS)

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