Products in Pharmaceutical Manufacturing: Binder

NEOSORB® XTAB 300S is a directly compressible sorbitol powder that can be used for very hard, sugar-free tablets with high flavor load. Benefits Delivers a smooth, hard and uniform colored surface Provides a clean, cooling effect Does not produce acids or cause dental plaque or tooth decay Nutritional benefits (maintenance of tooth mineralization, tooth-friendly generic EU claims) recognized by European regulations Features Non-cariogenic Sugar-free

XYLISORB® Xylitol powders are used in coatings for pharmaceutical and nutraceutical formulations, and as a filler, filler/binder and bulk sweetener that provides nutrient benefits. Applications Swallowable tablets Medicated confectionery Features Five-carbon polyol with a characteristic crystalline shape Low-calorie, sugar-free ingredient with high natural sweetness Suitable for use in formulations addressing pediatric and diabetic patient populations

Kollicoat® IR is a versatile pharmaceutical excipient for various applications. This polyvinyl alcohol-polyethylene glycol copolymer serves as a reliable binder, film former, matrix-forming agent, and emulsifier. Ideal for drug delivery and care solutions, it finds application in oral, topical, and transdermal formulations. In pharmaceutical manufacturing, it excels as an excipient for coatings. In solid powder form, Kollicoat® IR Kosher offers efficiency across healthcare and pharma technologies, catering to the ever-evolving demands of the pharmaceutical and nutraceutical industries.

Kollidon® VA 64 Coviplas serves as an anti-crystallizing agent, binder, filler, film former, matrix-forming agent, and solubilizer within the field of pharmaceuticals and nutraceuticals. It is available in powder form. This product is utilized in various pharmaceutical manufacturing applications and pharmaceutical processing.

Kollidon® 25 SD3 serves various functions such as an anti-crystallizing agent, binder, filler, matrix-forming agent, and solubilizer. It is available in powder form and falls under the domain of pharmaceutical and nutraceuticals technologies. This product finds applications in other pharmaceutical manufacturing processes and pharmaceutical processing.

Kollicoat® Protect is a versatile polyvinyl alcohol-polyethylene glycol copolymer designed for pharmaceutical and nutraceutical applications. Serving as a binder, emulsifying agent, film coating agent, and more, it excels in drug delivery and care solutions. This powder, utilized in oral, topical, and transdermal applications, stands out in pharmaceutical manufacturing as an excipient and coating. With its matrix-forming and taste-masking capabilities, Kollicoat® Protect ensures efficient and reliable performance. Its multifunctional nature extends to being a moisture barrier coating, enhancing its value in healthcare.

Kollidon® VA 64 Nub2 serves multiple functions as an anti-crystallizing agent, binder, filler, film former, matrix-forming agent, and solubilizer in the pharmaceutical and nutraceutical domains. It is available in powder form and is extensively utilized in various pharmaceutical manufacturing applications and pharmaceutical processing. This product is predominantly used in the healthcare and pharma markets, showcasing its versatility in diverse applications within the pharmaceutical industry.

Kollidon® 30 SD3 functions as an anti-crystallizing agent, binder, filler, film former, matrix-forming agent, and solubilizer. It falls under the domain of pharmaceutical and nutraceutical technologies. This product finds applications in various pharmaceutical manufacturing processes and other pharmaceutical manufacturing applications.

Kollidon® 30 S performs various functions, such as acting as an anti-crystallizing agent, binder, filler, film former, matrix-forming agent, and solubilizer. This product is available in powder form and is utilized in various pharmaceutical manufacturing applications and pharmaceutical processing. It falls under the domain of pharmaceutical and nutraceutical technologies.

T-Det® PEG 4000 F is a water-soluble polymer made from ethylene oxide. It has a wide range of applications as a humectant and viscosity modifier in the cosmetic and personal care industries, a mold release agent and lubricant in the rubber industry, and a binder and dry lubricant for pill and tablet manufacture in the pharmaceutical industry.

MASCEROL™ Glycerine 99.7 USP, non-GMO, RSPO MB is highly refined with a minimum glycerol content of 99.7%. MASCEROL™ Refined Glycerine is used as a base ingredient in personal care preparations. It provides moisturizing properties and improves skin permeability. It is a gentle ingredient for anti-aging and anti-irritant cosmetics found in skin and hair care applications, shaving cream, soaps, and water-based lubricants. MASCEROL™ Refined Glycerine is used as an excipient in pharmaceutical production and preparations for improving smoothness, providing lubrication, and because of its humectant characteristics. It is also found in allergen immunotherapies, cough syrups, tinctures, elixirs, and expectorants. It is a tablet-holding agent and a key ingredient in soft gelatin capsules. In food as well as beverage applications, MASCEROL™ serves as a humectant or wetting agent, solvent, sweetener, or sugar substitute (approximately 60% as sweet as sucrose), thickening agent, or filler.

MASCEROL™ Glycerine 99.7 USP, non-GMO is highly refined with a minimum glycerol content of 99,7%. MASCEROL™ Refined Glycerine is used as a base ingredient in personal care preparations. It provides moisturizing properties and improves skin permeability. It is a gentle ingredient for anti-aging and anti-irritant cosmetics, found in skin & hair care applications, shaving cream, soaps & water-based lubricants. MASCEROL™ Refined Glycerine is used as an excipient in pharmaceutical production and preparations for improving smoothness, providing lubrication, and because of its humectant characteristics. It is found in allergen immunotherapies, cough syrups, tinctures, elixirs & expectorants. It is a tablet-holding agent and a key ingredient in soft gelatin capsules. In food as well as beverage applications MASCEROL™ serves as a humectant or wetting agent, solvent, sweetener or sugar substitute (approx. 60 % as sweet as sucrose), thickening agent, or filler.

METOLOSE® SM 25 consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) each available in several grades differing in viscosity.

METOLOSE® consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) . METOLOSE SB-4 is an excellent sugar coating binder for solid dosage forms.

TYLOPUR® is a versatile hypromellose, compliant with USP, JP, EP. TYLOPUR 60SH-13000 provides a genuine consistency in Sustained release (matrix tablets). It also can be used as thickener in aqeous solution .

METOLOSE® SM 400 consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) each available in several grades differing in viscosity.

METOLOSE® SM 4 consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) each available in several grades differing in viscosity.

METOLOSE® SM 1500 consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) each available in several grades differing in viscosity.

Capsules prepared from hypromellose have advantages in comparison with gelatin based capsules. Hypromellose capsules show a better moisture stability and are suitable for vegetarian/vegan patients. Low viscosity hypromellose products like METOLOSE 65SH-5 is suitable for capsule manufacturing.

METOLOSE® SM 15 consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) each available in several grades differing in viscosity.

METOLOSE® SM 4000 consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) each available in several grades differing in viscosity.

METOLOSE® 65SH-1500 consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) each available in several grades differing in viscosity. METOLOSE® 65SH-1500 provides a variety of functions such as water retention, protective colloid, surface activity, sustained release. It is a non-ionic compound resistant to salting out and stable over a wide pH-range. Typical applications of METOLOSE® 65SH-1500 are binder for solid dosage forms such as tablets and granules or thickener for liquid applications.

METOLOSE® SM 100 consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) each available in several grades differing in viscosity.

Tylopur ClearCoat Nutra® provides a multifunctional coating that not only provides brilliant, transparent and shiny finish to your nutraceutical tablets but additionally protects them against humidity and friability. Moreover, coating with Tylopur ClearCoat Nutra® improves tablets’ swallowability.

TYLOPUR Xtend Nutra® is a plant derived ingredient (high viscous hydroxypropyl methylcellulose, HPMC) that has been developed by Shin-Etsu to provide a controlled, extended release of active compounds over a longer period of time, prolonging their effects on human body. TYLOPUR Xtend Nutra® acts as a hydrophilic matrix agent in hydrophilic matrix system, which is the simplest sustained release technology, consisting essentially of an active compound and a water soluble highly viscous natural polymer. Such a system allows a simple and straight forward direct compression formulation and a reduction of doses per day. It is not only cost effective but it is also consumer friendly. The mechanism of action of TYLOPUR Xtend Nutra® in hydrophilic matrix tablets consists of initial swelling caused by the hydration of a tablet, protective gel formation, which regulates the degree of active compound’s release, and time-related extended release of an active compound through the gel layer.

Tylopur ClearCoat Nutra® provides a multifunctional coating that not only provides brilliant, transparent and shiny finish to your nutraceutical tablets but additionally protects them against humidity and friability. Moreover, coating with Tylopur ClearCoat Nutra® improves tablets’ swallowability.

TYLOPUR Xtend Nutra® is a plant derived ingredient (high viscous hydroxypropyl methylcellulose, HPMC) that has been developed by Shin-Etsu to provide a controlled, extended release of active compounds over a longer period of time, prolonging their effects on human body. TYLOPUR Xtend Nutra® acts as a hydrophilic matrix agent in hydrophilic matrix system, which is the simplest sustained release technology, consisting essentially of an active compound and a water soluble highly viscous natural polymer. Such a system allows a simple and straight forward direct compression formulation and a reduction of doses per day. It is not only cost effective but it is also consumer friendly. The mechanism of action of TYLOPUR Xtend Nutra® in hydrophilic matrix tablets consists of initial swelling caused by the hydration of a tablet, protective gel formation, which regulates the degree of active compound’s release, and time-related extended release of an active compound through the gel layer.

METOLOSE® 60SH-10000 is used as a sustained-release agent, thickener, suspending agent and binder for tablets and granules. It is lso used for ophthalmic formulations.

METOLOSE® 90SH-100000 is used as a sustained-release agent, thickener, suspending agent and binder for tablets and granules. It is lso used for ophthalmic formulations.

METOLOSE® 65SH-4000 is used as a sustained-release agent, thickener, suspending agent and binder for tablets and granules. It is lso used for ophthalmic formulations.

METOLOSE® 60SH-4000 is used as a sustained-release agent, thickener, suspending agent and binder for tablets and granules. It is lso used for ophthalmic formulations.

METOLOSE® 60SH-50 is used as a sustained-release agent, thickener, suspending agent and binder for tablets and granules. It is lso used for ophthalmic formulations.

PHARMACOAT® 606 is a binder, it does not interact with drugs. It has superior stability, a non-ionic character and is widely used as a binder for granulation. Due to its plant derived nature and excellent moisture stability, PHARMACOAT®® replaces gelatin in hard capsule manufacturing. It is also used as taste making agent for bitter tasting drugs.

TYLOPUR® 606 is a versatile hypromellose, compliant with USP, JP, EP. It is a film coating material that provides an excellent finish.It is a effective binder, it does not interact with drugs.It also enhances the solubility of poorly solule APIs.

TYLOPUR® 645 is a versatile hypromellose, compliant with USP, JP, EP. It is a film coating material that provides an excellent finish.It is a effective binder, it does not interact with drugs.It also enhances the solubility of poorly solule APIs.