Brands in Solvents & Solubilizers

Kollisolv® composed of both hydrophilic and lipophilic excipients, the Kollisolv® portfolio of excipients is focused on addressing API solubility challenges. Available in liquids, semi-solids, and solids, these solubilizers and solvents are primarily used for oral and topical applications.

Kollidon® grades are processed via melt granulation, spray drying, and HME, these materials are suitable for a variety of formulations. Whether the target formulation is a tablet or transdermal patch, the Kollidon® family of multifunctional excipients is ready to resolve any formulation challenge. Kollidon® excipients come in various grades, giving you the flexibility to tailor your formulation based on your individual needs.

CAVAMAX® is the trade name for cyclodextrins from WACKER. We are the only company in the world to manufacture all three naturally occurring cyclodextrins – α, β and γ (CAVAMAX® W6, W7 and W8). CAVAMAX® cyclodextrins have unique properties resulting in a wide range of functionalities, such as stabilization, rheology control, masking of bitterness or increasing bioavailability and much more. This paves the way for innovative food, pharma and industrial applications.

Soluplus® Offers outstanding solubilization properties, this novel excipient is ideal for poorly soluble APIs. It is applicable for oral solid dosage forms, topical polymeric films, transdermal patches, and solutions.

Kollicoat® polymers can also be used for taste masking to improve patient compliance. While these excipients are predominantly used for oral applications, coating polymers can also be utilized for the development of topical films and transdermal patches as film and matrix formers, respectively. The Kollicoat® family of coating polymers consists of a broad range of chemistries to address various film coating challenges.

Kolliphor® grades are used in oral, topical, and parenteral dosage forms, these excipients simplify the formulation process by exerting their versatile functionalities. The Kolliphor® family of solubilizers, emulsifiers, co-emulsifiers, and surfactants are ideal for addressing solubilization challenges to inhibit crystallization and enhance drug bioavailability.

These polyglycerol esters (PGEs) function as EO-free surfactants and solubilizers in an array of applications because they offer a wide range of HLBs. In addition, they offer other benefits such as: improves texture and consistency, works well to improve flow properties, stabilizes aerated systems by controlling the agglomeration of fat globules, reduces interfacial tension at oil-water boundaries.

Kollicream® grades are either comprised of esters of fatty acids (3 C, CP 15, DO, IPM), or of natural (OA), as well as naturally derived (OD) long-chain alcohols. Except for CP 15, which is provided in the form of waxy pellets, all other members of the Kollicream® family, as well as Kollisolv® MCT 70, are transparent, colorless liquids at room tempreature. The raw material base is coconut oil, and/or palm kernel oil.

Acconon products are well-characterized mixtures of polyoxyethylene mono- and diglycerides, fatty acids or fatty alcohols. In addition to functioning as excellent oil/water emulsifiers, many of these products can add emolliency to creams and lotions. Our line includes alkoxylates based on natural oils such as coconut, castor, and apricot oil.

CAPMUL® multi-functional, high purity monoesters provide superior skin penetration and emolliency with excellent effects against microorganisms. Certain grades of CAPMUL® may be used to inhibit the growth of gram positive and negative bacteria, yeast, and mold in many "preservative free" products. They are used to produce stable emulsions, to modify viscosity and they can act as carriers and vehicles in selected applications.

Captex® Medium-Chain Triglycerides originate from renewable vegetable-based sources (typically palm, palm kernel and/or coconut). These food-grade, safe, responsibly sourced ingredients are best known for their functional benefits as emulsifiers, solubilizers and refatting agents for use in a range of markets and applications including, personal care, cosmetics, food, and nutritional supplements. Additionally, these products boast numerous health benefits in areas such as weight management, energy, and cognition.ABITEC offers a variety of C8 (caprylic) and C10 (capric) variations to suite your formulation requirements.

CLEARGUM® are thin-boiling or octenyl succinate starches

KLEPTOSE® Beta-cyclodextrins are efficient solubilizers, stabilization enhancers and taste-masking agents. A full range is available for use in many dosage forms, from solid to liquid. Molecular encapsulation with beta-cyclodextrins is an accepted and useful tool for pharmaceutical formulators, with many pharmaceutical products containing cyclodextrin complexes on the market. Roquette has developed a wide range of KLEPTOSE® offering features like low water content, various particle size and directly compressible properties with KLEPTOSE® DC. Roquette has pioneered the industrial development of cyclodextrins with its KLEPTOSE® range of beta-cyclodextrins. KLEPTOSE® can be used in various oral dosage forms in both pharmaceutical and nutraceutical applications including swallowable tablets, chewable tablets, effervescent tablets, lozenges, hard capsules, soft capsules, orally dissolving films, blends, granules, pellets premix, medicated confectionary, syrups, suspensions and liquids.