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Glydant® is a preservative system that provides excellent bactericide and mild fungicide for product protection. This cost-effective, water soluble system can be easily incorporated into a broad number of personal care products and offers water-white/color stability, heat stability, and compatibility with anionic, nonionic and cationic systems.

INCI Name: DMDM Hydantoin

Functions: Anti-Microbial Agent, Bacteriostatic Agent, Fungistatic Agent, Preservative

Benefit Claims: Anti-Bacterial, Anti-Fungal, Color Stability, Compatibility, Cost Effective, Easy To Use, Excellent Flexibility, Heat Stability, Low Viscosity, Preservation

Labeling Claims: Environmentally Friendly, Halal, Natural, Non-GMO, Organic, Sustainable, Ulta Beauty's Conscious Beauty

Certifications & Compliance: EU Compliant, EU Cosmetic Regulation 1223/2009 Compliant, Halal, IECIC (China)

Technical Data Sheet
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Knowde Enhanced TDS

Identification & Functionality

CAS No.
6440-58-0
EC No.
229-222-8
Compositional Breakdown
Chemical Compound Breakdown Cas No. EINECS No.
DMDM Hydantoin 6440-58-0 229-222-8
Water 7732-18-5 231-791-2

 

Chemical Compound Breakdown %
DMDMH 54-56%
Water 44-46%

Features & Benefits

Key Attributes
  • Excellent antibacterial, mild antifungal
  • Water-based solution of DMDM Hydantoin
  • Suitable for a broad range of rinse-off and leave-on applications
  • Extremely cost-effective
  • Has a wide range of global regulatory approval
  • Formulation flexibility
  • Water-white/color stability
  • Compatibility with anionics, nonionics and cationics
  • Heat stability
  • Water solubility

Applications & Uses

AP/Deo Applications
Baby Care Applications
Bath & Shower Applications
Personal Hygiene Applications
Wipes, Tissue & Towel Applications
Use Level
0.1-0.6%
Application pH Range
2–10
Formulation Recommendations
  • Wide pH range: 3–10
  • Compatible with anionic, cationic and nonionic systems
  • Add during cool down phase of process, where possible
  • Short bursts of temperature are also acceptable, up to 80°C, in closed systems

Properties

Physical Form
Odor
Low Characteristic
Soluble in
Water

Regulatory & Compliance

Chemical Inventories
Global Regulatory

Europe

  • Approved under Annex V to Regulation EC/1223/2009
  • Finished products containing DMDMH must be labeled with the warning “contains formaldehyde” if the (free) formaldehyde concentration exceeds 0.05%
  • Maximum concentration 0.6% DMDMH

Japan

  • Listed in the positive list
  • The following warning must be labeled: “should not be used by infants or by people who are hypersensitive to formaldehyde.”
  • Can be used at a level up to 0.3% DMDMH for rinse-off only
  • Not permitted for oral care

United States

  • Approved by CTFA for both rinse-off and leave-on applications; can be used at a level up to 0.6% DMDMH

General

  • Not for use in oral and lip products

Technical Details & Test Data

Efficacy

Microbiological Challenge Studies
Studies were run using various concentrations of Glydant® 2000, a lower formaldehyde variant in the Glydant range, in a shampoo formulation to see efficacy on a mixed inoculum of bacteria and mixed fungi. All samples were inoculated at the beginning of the study, sampled at 24 hours, 3, 7, 14, 21 and 28 days.

Challenge Test Data in a Protein Shampoo
Ingredient % wt/wt
Sodium Laurylethersulfate 35.0
Triethanol Laurylsulfate 25.0
Cocodiethanolamide 3.0
Water, DI 36.0
Anhydrous protein 1.0
Preservative q.s.
Total 100

 

Organism count (cfu/ml) / Contact time (days)
Test Organisms 0 7 14 21 28
Mix Bacteria Glydant® 0.05% 1.5 x 10^6 < 10 < 10 < 10 < 10
Glydant® 0.1% 1.5 x 10^6 < 10 < 10 < 10 < 10
Glydant® 0.2% 1.5 x 10^6 < 10 < 10 < 10 < 10
Mix Fungi Glydant® 0.1% 6.6 x 10^5 1.6 x 10^3 1.6 x 10^3 1.0 x 10^3 3.6 x 10^2
Glydant® 0.2% 6.6 x 10^5 < 10 < 10 < 10 < 10
Glydant® 0.4% 6.6 x 10^5 < 10 < 10 < 10 < 10

Packaging & Availability

Country Availability
Regional Availability
  • Africa
  • China
  • Europe
  • India
  • Japan
  • Latin America
  • Middle East
  • North America
  • Oceania
  • South East Asia