Knowde Enhanced TDS
Identification & Functionality
- Ingredient Origin
- Cosmetic Ingredients Functions
- Technologies
- Product Families
Features & Benefits
- Benefit Claims
- Labeling Claims
- Key Attributes
- Has a wide range of global regulatory approvals
- Unique and cost effective preservative
- Synergistic combination of two well-trusted preservatives
- Combination with a dual mode of action
- High level of antimicrobial activity in a wide variety of cosmetic and personal care formulations (“wash-off “ or “leave-on” products)
- Highly effective in inhibiting the growth of gram positive and gram negative bacteria, yeasts and molds without the need of additional auxiliary preservatives
- Remains stable for extended periods of time over wide pH and temperature ranges
- Low odor
- White granular product
- Effective blend of DMDMH and IPBC
- Lower amount of preservative required
- Several modes of action
- Lower risk of microbial resistance
Applications & Uses
- Markets
- Applications
- AP/Deo Applications
- Color Cosmetic Applications
- Hair Care Applications
- Personal Hygiene Applications
- Skin Care Applications
- Sun Care Applications
- Use Level
- 0.075–0.18%
- Application pH Range
- 2–10
- Applications
- Anhydrous
- Baby care (rinse-off only)
- Conditioner
- Cream
- Deo / Anti-perspirant
- Eye creams/gels
- Eye shadow
- Face lotion
- Face wipes
- Facial cream
- Foundation
- Hair gel
- Hand soap
- Lotion
- Make up remover
- Mascara
- Oil in Water
- Powder
- Shampoo
- Suncare
- Toner
- Water in Oil
Properties
- Odor
- Characteristic
- Appearance
- Granular
- Soluble in
- Water
- Compositional Breakdown
Chemical Compound Breakdown Percentage DMDMH range 94–96 % 3-Iodo-2-propynylbutylcarbamate 4.5–5.5 %
Regulatory & Compliance
- Certifications & Compliance
- Chemical Inventories
- Global Regulatory
Europe
- Both active ingredients approved, Annex V to Regulation EC/1223/2009.
- Finished products containing DMDMH must be labeled with the warning “contains formaldehyde” if the (free) formaldehyde concentration exceeds 0.05%
- Max use level: 0.6% DMDMH and 0.01% IPBC (leave-on except in creams and lotions aimed to be applied on a large part of the body), 0.6% DMDMH and 0.02% IPBC (rinse-off). Allowed in rinse- off products up to 0.02% IPBC and up to 0.01% IPBC
- Not allowed for oral and lip products
- Cannot be used in products for children under three years (except for rinse-off)
Japan
- Listed in the positive list. The following warning must be labeled: “should not be used by infants or by people who are hypersensitive to formaldehyde.”
- Cannot be used in leave-on due to DMDMH
- Max use level: 0.3% DMDMH and 0.02% IPBC for rinse-off
- Not permitted in oral care
USA
- Approved by CTFA for both rinse-off and leave-on applications
- Max use level of 0.6% DMDMH and 0.01% IPBC
Technical Details & Test Data
- Efficacy
Microbiological Challenge Studies
Studies were run using different concentrations of Glydant Plus® in various formulations to see efficacy against various bacteria, yeast and fungi. All samples were inoculated at the beginning of the study, sampled at 24 hours, 3, 7, 14, 21 and 28 days.
Glydant Plus® was incorporated into a glyceryl monostearate cream (GMS), a standard medium used for efficacy studies.- Heat Stability
Glydant Plus® at 0.1% in a GMS Cream at an accelerated aging temperature of 45°C for 42 days.
Test Organism CFU/days Day 0 Day 7 Day 14 Day 21 Day 28 Candida albicans 20000 <10 <10 <10 <10 Pseudomonas aeruginosa <10 <10 <10 <10 <10 Control >106 >106 >106 >106 >106
Packaging & Availability
- Country Availability
- Regional Availability