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Proxel® TN Preservative

1 of 25 products in this brand
Proxel® TN Preservative is a dual active, broad spectrum biocide for the preservation of industrial water-based products against spoilage from bacteria, yeasts and fungi. It is a 55% aqueous solution of 1,2-benzisothiazolin-3-one (BIT) and hexahydro-1,3,5-tris(2-hydroxyethyl)-s-triazine, a formaldehyde release agent. It is effective in a wide range of industrial aqueous-based products. The combination of two active agents provides a quick microbial kill with long term protection. The “triazine” active agent gives enhanced head space protection in the container.

Functions: Anti-Microbial Agent, Anti-Microbial Agent, Bactericide, Biocide, Preservative

Features: Bacteria Resistance, Fungal Resistance

Synonyms: 1,2-Benzisothiazol-3-one, 1,2-Benzisothiazolin-3-one, 1,2-Benzisothiazolone, 1,2-Benzoisothiazol-3-one, 1,2-benzothiazolin-3-one, 1,2-benzothiazoline-3-one, 2,3-Dihydro-1,2-benzothiazol-3-one, 2,3-Dihydrobenzisothiazol-3-one, 3-Hydroxy-1,2-benzisothiazole, Benzisothiazolin-3-one, Benzisothiazolinone, Benzisothiazolone, Benzo[d]isothiazol-3(2H)-one, Benzoisothiazol-3-one

    Knowde Enhanced TDS

    Identification & Functionality

    Carrier
    CAS No.
    2634-33-5
    EC No.
    220-120-9
    Chemical Structure

    Proxel® TN Preservative - Chemical Structure

    Composition

    An aqueous solution of 1,2-benzisothiazolin-3-one and hexahydro-1,3,5-tris(2 hydroxyethyl)-s-triazine

    Features & Benefits

    CASE Ingredients Features

    Applications & Uses

    Applicable Processes
    Adhesive & Sealant Type
    Coating Type
    Use Level
    0.01-0.30%
    Applications

    The product is effective in a wide range of industrial aqueous-based products. The combination of two active agents provides a quick microbial kill with long term protection. In addition, the “triazine” active agent gives enhanced head space protection in the container. Application areas include:

    • Synthetic polymer emulsions
    • Emulsion paints
    • Aqueous pigment dispersions
    • Water-based adhesives
    Amount to Use

    Table 3. Applications

    Product % PROXEL™ TN Preservative (w/w)
    Emulsion Paints 0.05-0.2
    Pigment dispersions: based on slurries 0.05-0.2
    Synthetic polymer emulsions 0.05-0.2
    Water-based adhesives 0.05-0.15

     

    PROXEL™ TN Preservative should be added to the system as early in the process as possible but only after all heating stages are completed and the temperature of the product is less than 40°C. The concentration required to adequately preserve your product depends on several factors. These include the susceptibility of the system to microbiological degradation, the extent to which micro-organisms can gain access, the species involved, pH, temperature, and length of time for which protection is required.


    A range of concentrations and applications is recommended in Table 3; however, it is recommended that a testing program be undertaken to determine the most costeffective dose for your application.


    Testing should take into account chemical compatibility/stability, plant hygiene conditions, susceptibility of the product to contamination, and the typical organisms involved.

    Properties

    Physical Form
    Soluble in
    Water
    Typical Physical Properties
    ValueUnitsTest Method / Conditions
    pH Value (25°C)12
    Viscosity (at 10/25°C)180/60mPasNewtonian
    Boiling Point110°C
    Flash PointBoils without flashing°C
    Density (at 25°C)1.13
    Minimum Inhibitory Concentrations (MIC)

    Table 1.

    Micro-organism PROXEL™ TN Preservative (ppm)
    Bacteria  
    Bacillus subtilis 100
    Enterobacter cloacae 150
    Escherichia coli 100
    Proteus vulgaris 175
    Pseudomonas aeruginosa 200
    Pseudomonas putida 200
    Staphylococcus aureus 100
    Strephylococcus faecalis 100
    Strephylococcus lactis 100
    Fungi  
    Alternaria alternata 1000
    Aspergillus niger 500
    Aureobasidium pullulans 750
    Chaetomium globosum 500
    Cladosporium cladosporioides 600
    Penicillium notatum 300
    Yeasts  
    Candida albicans 150
    Rhodotorula rubra 200
    Saccharomyces cerevisiae (turbindans) 150

     

    Antimicrobial Properties

    The levels of product needed to prevent the growth of problem microorganisms are listed in Table 1; Minimum Inhibitory Concentrations (MICs) do not represent effective use levels but do indicate the broad spectrum of activity.

    PROXEL™ TN Preservative has a non-specific mode of action which means that bacterial resistance is very unlikely to occur. Detailed information on the mode of action is available on request.

    Active Agent

    50% w/w “triazine” and 5.5% w/w 1,2-benzisothiazolin-3-one

    Compatibility

    Compatible and effective over pH range 4-12. Stable in the presence of amines.
    Incompatible with some oxidizing and reducing agents e.g. persalts, sulphites etc.

    Regulatory & Compliance

    Certifications & Compliance
    Total Quality

    Lonza Microbial Control holds a number of ISO 9001 Quality Management registrations covering our product range. The scope of each registration is specific to the location or entity named on the Registration Certificate and our products are supplied to ISO 9001 Standards.

    Regulatory Information

    The components of PROXEL™ TN Preservative are in compliance with the following inventories:

    • EINECS (Europe)
    • TSCA (USA)
    • AICS (Australia)
    • ENCS (Japan)
    • DSL (Canada)
    • KECL (Korea)
    • PICCS (Philippines)
    • IECSC (China)

    Safety & Health

    Risk Assessment and Management

    Lonza professionals have a wide expertise in the fields of Safety, Health and the Environment. Lonza Microbial Control is committed to and uses this expertise in understanding the suitability of PROXEL TN Preservative for specific applications

    Packaging & Availability

    Regional Availability
    • Africa
    • China
    • Europe
    • India
    • Japan
    • Latin America
    • Middle East
    • North America
    • Oceania
    • South East Asia

    Storage & Handling

    Storage & Stability

    Stable under normal conditions of storage down to -10°C. If frozen, allow to thaw and stir well before use.