Products

Pleiotanicals® Volpura® EP (R10098) is an Echinacea purpurea extract to address the signs of aging by supporting the skin’s natural plumping processes. Volpura® EP activates adipogenesis (fat production) within the skin to combat the appearance of wrinkles and sagging from deep within the tissue. Volpura® EP restores fuller, youthful-looking skin by activating an adipogenic modulator that increases the number and size of fat-producing cells. Clinical studies demonstrate that Volpura® EP improves skin mechanical properties with volumizing, anti-wrinkle activity reported after use on the face and hands for 12 weeks. Volpura® EP is recommended for anti-wrinkle, anti-aging, firming, plumping, topical contouring, and volumizing products, as well as regimens to address age-related lipoatrophic disorders.

DermalRx® CKW (R10091) is a plant-derived combinatorial curcuminoid extract that potently and dose-dependently modulates excess sebum production by inhibiting type I and type II 5α-reductase. Clinical evaluation showed significant reductions in sebum production and a visible decrease in facial sheen. DermalRx® CKW is ideal for sebum-regulating products for skin and hair applications, as well as anti-blemish and pore-minimizing formulations.

Tellirictin® (R10047) is a proprietary clove flower extract containing natural gallate-based pleiotropic compounds (tellimagrandin I and casuarictin) for multi-functional anti-aging performance. Tellirictin® addresses the many signs of aging by delivering brightening, anti-wrinkle, and moisturizing activities, while also protecting the skin from oxidative, inflammatory, proteolytic, and environmental stresses. Applications of Tellirictin® include anti-aging, anti-wrinkle, and skin-brightening regimens, soothing and calming products for sensitive skin, and pre- and post-sun care.   Tellirictin® prevents excessive melanin production to combat hyperpigmentation by inhibiting tyrosinase activity as efficiently as beta-arbutin. Tellirictin® protects collagen and other components of the extracellular matrix (ECM, the structural foundation of the skin) from damaging enzymes (MMPs and elastases) associated with environmental stressors such as environmental pollution and UV (sun) exposure. Tellirictin® modulates microRNAs involved in the beneficial regulation of DNA repair, barrier protection, and anti-inflammatory pathways. 

HEDI® Mango Butter (R10076) is a unique water-based dispersion of mango butter with babassu oil, squalane, and vitamin E in a silicone-free microdispersion carrying more than 30% hydrophobe. HEDI® Mango Butter is a plant-derived alternative for paraffin and silicone-based emollients. Applications for HEDI® Mango Butter include moisturizing treatments for very dry, rough, and cracked skin, skincare products for sensitive skin, and skin, scalp, and hair care conditioning formulas. A soft solid with a very slight sweet scent, Mango Butter exhibits excellent moisturizing properties and good lubricity. Mango Butter, obtained from de-shelled fruit kernels of the mango tree, has natural antioxidant, anti-inflammatory, and antimicrobial properties. Organic certified babassu oil is extracted from wild-picked fruits of the babassu palm tree, offering softening properties with glycerides of lauric, myristic, and oleic acids. HEDI® products are stable ingredient blends of aqueous and oil-based materials made using a unique manufacturing process. HEDI® products are ultra-concentrated homogeneous constructs that are infinitely dilutable in aqueous systems. HEDI® products have superior aesthetics while simplifying formulation and manufacturing processes and enhancing the delivery of active ingredients in the formula. HEDI® products can be adjusted to achieve a consistency that is milk-like (pourable and even sprayable), creamy, or paste-like. Tactile properties can be light and silky or velvety and more occlusive. HEDI® products streamline manufacturing processes for time, energy, and cost savings by avoiding additional heating, melting, and mixing steps. HEDI® products are amenable to cold processes and do not require surfactants or emulsifiers.HEDI® products have properties similar to the skin barrier, promoting skin permeability and facilitating delivery through the lipid-rich, waterproof stratum corneum. Finished products have a better feel and provide superior surface coverage when compared to traditionally formulated butters and oils.

Pleiotanicals® Ellagicin®(R10068) is a botanically derived active ingredient containing proprietary acai and pomegranate “superfruit” extracts for antioxidant and anti-aging benefits. Ellagicin® is rich in ellagic acid, anthocyanins, and other natural antioxidants that provide protection from oxidative and proteolytic stress. Ellagicin® protects collagen and other components of the extracellular matrix (ECM, the structural foundation of the skin) from damaging enzymes associated with environmental stressors such as environmental pollution and UV (sun) exposure. Applications of Ellagicin® include anti-aging and anti-wrinkle regimens, soothing and calming products for sensitive skin, and pre- and post-sun care.

DermalRx® FSE (R10111) is a marine bioferment produced from Sargassum vulgare for DNA protection and repair in sun-exposed skin. Rich in bioactive phlorotannins, DermalRx® FSE stimulates the skin’s natural DNA repair process through nucleotide excision repair (NER). Ex vivo studies demonstrate DermalRx® FSE’s DNA protective and reparative effects after UV exposure. DermalRx® FSE also provides strong anti-pollution activity, protecting the skin from damaging oxidation and inflammation. DermalRx® FSE is ideal for anti-aging, de-stressing, soothing and calming, and pre- and post-sun care products.

Pleiotanicals® Volpura® EPO (R10125) is a plant-derived active ingredient extracted from Echinacea purpurea, known for its abundance in various active compounds, notably fatty acid alkylamides. This ingredient demonstrates the ability to activate PPAR-γ, which serves as the master regulator of adipogenesis. Its benefits lie in enhancing fat production by stimulating the differentiation of pre-adipocytes into adipocytes. This property makes it suitable for incorporation into formulations targeting anti-wrinkle effects, particularly for addressing expression lines in the forehead and nasolabial fold areas. Additionally, it finds application in facial contouring, re-firming, and plumping regimens aimed at addressing age-related lipoatrophy.