CompactCel® DIS

Identification & Functionality

Chemical Family

Cellulose & Cellulosics

Pharma & Nutraceuticals Functions

Disintegrant

Technologies

Pharmaceuticals & Nutraceuticals

Product Families

Pharmaceuticals & Nutraceuticals — Excipients

Binders & Disintegrants,

Modified & Controlled Release

Pharmaceuticals & Nutraceuticals — Processing, Purification & Testing Solutions

Other Raw Materials

Features & Benefits

Labeling Claims

Clean Label,

Magnesium Stearate-free,

Organic,

Palm Oil-free,

Silica-free,

Silicon dioxide-free,

Synthetic Polymers-free,

Talc-free,

Titanium dioxide-free

Product Information

• CompactCel® DIS is a natural/organic super-disintegrant which enables a rapid break-up of solid dosage forms when they come into contact with moisture.
• The super-disintegrant premix is formulated with natural ingredients and complies with current Clean Label standards. It provides an alternative to synthetic super-disintegrants, such as crosslinked polymers, crosscarmellose sodium or sodium starch glycolate.
• CompactCel® DIS helps in the fast breakdown of the solid dosage form so that the active ingredient becomes bioavailable faster and is readily absorbed. It can also be used in the formulation of oral disintegrating tablets (ODT) or chewing tablets.

Product Features

CompactCel® DIS for direct compression possesses several useful properties:

• Good hydration
• Poor gel formation
• Good compressibility and
• Flow property
• Faster therapeutic effect
• Neutral odor and practically tasteless

Applications & Uses

Markets

Food & Nutrition,

Healthcare & Pharma

Applications

Healthcare & Pharma — Drug Delivery & Care Solutions

Oral

Food & Nutrition — Nutrition & Well Being

Nutraceuticals & Supplements

Healthcare & Pharma — Pharmaceutical Manufacturing

Excipients & Coatings

Dosage Form

Capsules,

Orally Disintegrating Tablets (ODTs),

Tablets

Manufacturing Technology

Direct Compression,

Tablet Coating

Food & Nutrition Applications

Dietary Supplements

Properties

Physical Form

Powder,

Solid

Odor

Neutral

Taste

Tasteless

Regulatory & Compliance

Certifications & Compliance

EXCiPACT,

European Pharmacopeia (Ph. Eur.),

ISO 9001,

Organic Certified,

USDA Organic,

United States Pharmacopeia (USP)

Grade

Pharma Grade

Technical Details & Test Data

Placebo Tablet Formulation with 3% Disintergrant

Disintegrants and super-disintegrants are used to increase the surface area of the tablet fragments and to overcome cohesive forces that keep particles together in a tablet. Without the disintegrant the active might not get dissolved quickly to correspond to the requirements of a fast release dosage form.

For improving the release characteristics, an incorporation rate of the CompactCel® DIS in the tablet formulation is recommended between 1-5%.

Placebo formulation : Isomalt, Gum arabic, Innulin, Root-claw extract