Knowde Enhanced TDS
Identification & Functionality
- INCI Name
- Ingredient Name
- Cosmetic Ingredients Functions
- Food Ingredients Functions
- Pharma & Nutraceuticals Functions
- CAS No.
- 480-18-2
- EC No.
- 207-543-4
- Product Families
Features & Benefits
- Benefit Claims
- Benefit Claims (Health)
- Food Ingredients Features
- Advantages of Taxifolin BC-DHQ®
- US FDA no objection to notification of self-armed GRAS (GRN No. 916)
- Sustainably produced using a proprietary bioconversion manufacturing process
- Non-GMO, vegan, and kosher
- Clean, reliable, and scalable production methods
- Available at 10% active
Applications & Uses
- Applications
- Food & Nutrition Applications
- Benefit Areas
- Antioxidant Support
- Taxifolin has a greater antioxidant capacity than vitamin C.
- Cellular Health
- Taxifolin may neutralize free radicals and prevent oxidative cellular damage.
- Immune Health
- Emerging evidence suggest that taxifolin may have immunomodulatory activity supporting its role in a healthy immune response.
- Respiratory Health
- A study in 112 subjects showed taxifolin as an adjuvant supported respiratory function.
- Skin Health
- In human skin cells, taxifolin performed better than retinoic acid in down- regulating MMP-1, an enzyme responsible for collagen degradation associated with sun exposure.
- Emerging evidence suggests oral taxifolin supplementation may support a healthy inflammatory response related to skin conditions.
- Food Preservation
- Taxifolin inhibited lipid peroxidation and possessed antioxidant activity similar to Trolox, α-tocopherol, BHT, and BHA.
- Superficial treatment of 0.2% or 0.5% taxifolin improved quality and shelf life of packaged meat and salmon respectively.
- Antioxidant Support
Regulatory & Compliance
- Certifications & Compliance
Technical Details & Test Data
- Scientific Studies
Antioxidant Activity
A study was conducted to evaluate the antioxidant and antiradical activities of taxifolin using different in vitro bioanalytical methods.- Design:
- Pure taxifolin was compared with other standard antioxidants including BHA, BHT, α-tocopherol, and Trolox
- Outcomes:
- Taxifolin demonstrated 81% inhibition of linoleic acid peroxidation at 30 μg/ml, which is similar to inhibition by other antioxidants
- Taxifolin also exhibited effective DMPD•+, ABTS•+, O2•- and DPPH• scavenging effects, reducing capabilities, and Fe2+ chelating effects.
Respiratory Health
A clinical study investigated the effect of oral taxifolin supplement as an adjuvant in men who suffered from acute compromised respiratory function.- Design:
- 112 subjects were divided into 3 groups: group 1 (n=50) received standard therapy, group 2 (n=32) received standard therapy plus α-tocopherol acetate and sodium thiosulphate, group 3 (n=30) received the standard therapy plus 40-60 mg of taxifolin four times a day
- Outcomes:
- Compared to controls, the group that received taxifolin supplementation showed a more rapid respiratory immune response, a tendency towards improved indicators of respiratory function, and increased levels of endogenous antioxidants
- Design: