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Macamin™ NC (Niacinamide) is vitamin B3, an essential nutrient. It provides both nutritional and topical benefits. As a skin care active, niacinamide can improve the appearance of hyperpigmented skin, reduce redness, fine lines and wrinkles, smooth skin texture and enhance skin barrier properties.

INCI Name: Niacinamide

Ingredient Name: Nicotinamide

Vitamin Type: Vitamin B, Vitamin B3

Ingredient Origin: Synthetic

Labeling Claims: 1,4-Dioxane-free, Allergen-free, Animal Products-free, BSE-free, Bisphenol A-free, Butylated Hydroxyanisole-free, CMR Substances-free, Clean at Sephora, Credo Clean Standard, Formaldehyde-free, Fragrance-free, Gluten-free, Glycol ether-free, Halal, Hormones-free, Kosher, Latex-free, Nanomaterials-free, Nitrosamines-free, Non-GMO, Non-Phenolic, Not Listed In California Proposition 65, Not Tested on Animals, Palm Oil-free, Palm free, Paraben-free, Petrochemical-free, Phthalates-free, Silicone-free, Soy-free, Sulfate-free, TSE-free, Talc-free, Ulta Beauty's Conscious Beauty

Certifications & Compliance: FCC Compliant, National Formulary (NF), United States Pharmacopeia (USP)

Knowde Enhanced TDS

Identification & Functionality

Country of Origin
INCI Name
Ingredient Name
Ingredient Origin
Food Ingredients Functions
Pharma & Nutraceuticals Functions
CAS No.
98-92-0
EC No.
202-713-4

Features & Benefits

Applications & Uses

Color Cosmetic Applications
Food & Nutrition Applications
Hair Care Applications
Suggested Use Level
4 - 5 %

Properties

Physical Form
Appearance
White Crystalline Powder
Soluble in
Water
Typical Properties
ValueUnitsTest Method / Conditions
Assay98.5 - 101.5%
Melting Point128 - 131°C
Optimal pH Value6
Chemical Composition
ValueUnitsTest Method / Conditions
Niacinamide Contentmin. 99%
Heavy Metals
ValueUnitsTest Method / Conditions
Arsenic Content0.001ppm
Cadmium Content0.001ppm
Lead Content0.03ppm
Mercury Content0.001ppm

Regulatory & Compliance

Technical Details & Test Data

Efficacy Testing

Niacinamide Effectively Reduces Appearance of Melasma, Comparable to Hydroquinone

Macamin™ NC - Efficacy Testing

Figure 1. Physicians Global Assessment of melasma improvement

  • Niacinamide appears to be a suitable alternative for treatment of melasma without the undesirable side effects of hydroquinone.
  • Five percent niacinamide reduces hyperpigmentation, fine lines and wrinkles and skin yellowing.
  • Five percent niacinamide gel is as effective as 2% clindamycin gel for treatment of acne vulgaris. Moreover, use of clindamycin may increase risk of development of antibiotic resistance whereas niacinamide does not.

Storage & Handling

Shelf Life
5 years
Storage Conditions

Store in a tight container