Knowde Enhanced TDS
Identification & Functionality
- Country of Origin
- INCI Name
- Ingredient Origin
- Vitamin Type
- Cosmetic Ingredients Functions
- CAS No.
- 68-26-8, 11103-57-4
- Technologies
Features & Benefits
- Benefit Claims
- Labeling Claims
Applications & Uses
- Markets
- Color Cosmetic Applications
- Skin Care Applications
- Use Level
- 0.01 - 0.3%
Properties
- Physical Form
- Appearance
- Oily, yellow liquid
- Typical Properties
- Chemical Composition
- Residual Solvents
- Note
* - Macamin™ RL50WME has been produced according to the guideline EMEA/CHMP/SWP/4446/2000 “Guideline on the specification limits for residues or metal catalyst or metal reagents”. No metal catalyst or metal reagents have been used during production. Accordingly, no tests concerning heavy metal residues were performed.
| Value | Units | Test Method / Conditions | |
| Concentrations | 45 - 55 | % | — |
| Value | Units | Test Method / Conditions | |
| Retinol Content | 45.0 - 55.0 | % | — |
| DL-α tocopherol Content | 1.2 - 2.2 | % | — |
| Polysorbate 20 Content | 44.0 - 54.0 | % | — |
| Value | Units | Test Method / Conditions | |
| Methanol Content (Class II)* | 3000.0 | ppm | — |
| Hexanes Content (Class II)* | 290.0 | ppm | — |
| n-Pentane Content (Class III)* | 5000.0 | ppm | — |
Regulatory & Compliance
Technical Details & Test Data
- Efficacy Testing Information
Reduction of Fine Wrinkles
Forty-one women with healthy, mature skin (ages 35-55) applied 0.1% retinol formulation to full face every other day for 12 weeks. Facial wrinkle analysis was conducted with full face images every 4 weeks.
Effect of topical retinol application on fine wrinkles
Representative data of 41 volunteers
Wrinkles decreased almost 59% around the cheeks by week 4, and almost 65% by week 12. Wrinkles decreased almost 28% around the eyes by week 4 and almost 40% by week 12.
Storage & Handling
- Shelf Life
- 1 year
- Storage Conditions
- Stable at room temperature.
- Sealed under Nitrogen 2 - 8°C