Blood Sugar Management via inhibition of Amylase Activity: Comparison of the effectiveness of White Kidney Bean Extract (WKBE] and PureSea® Seaweed
Background : Research on White Kidney Bean Extract has shown it to be effective at inhibiting amylase activity, which reduces the rat of carbohydrate digestion and blood sugar release* (as shown in the graph to the right). This demonstrates beneficial effects for weight loss and blood sugar management. Similarly, research on PureSea® seaweed shows significant reduction in the rate of digestion of carbohydrates through the same mechanism**. These findings formed the basis of the present independent analysis, which aimed to establish which of the two (WKBE or PureSea® seaweed] was the most effective at inhibiting amylase activity.
Method : In vitro comparison of WKBE and PureSea® seaweed in an amylase activity assay.
Key findings :
- The rate of amylase inhibition of PureSea® was found to be over 5 times higher than that of WKBE
- Dose response data demonstrated that PureSea® was significantly more effective at reducing amylase activity from concentrations of 1.25mg/ml to 10.0mg/ml
- The most effective dose response of PureSea® (5mg/ml] reduced amylase activity by 96.1%
Comparison of 1.5g of WKBE vs. control on changes in plasma glucose after carbohydrate consumption (*significance vs. control)
Amylase dose response activity curve in the presence of PureSea® seaweed or WKBE.
Conclusion : Research comparing the impact of PureSea® seaweed and WKBE on amylase activity has demonstrated that PureSea® is significantly more effective at inhibiting amylase. These findings indicate that PureSea® could be a more effective choice than its well-known counterpart — which has a strong market presence - at inhibiting carbohydrate breakdown and reducing the rate at which sugar is released into the blood.
Application: Scaling the in vitro dose into a real-world scenario would equate to a daily dosage of 250-500mg of PureSea® Natural, which could result in an impact of reduced carbohydrate breakdown and slower blood sugar release.