Products in Excipients & Coatings

BIOGRUND provides a wide range of film coating products which includes Bonulac®. It's a nutritional enteric coating product. It provides a protective film with excellent moisture sealing and enteric properties. With its superior taste and moisture protection it is recommended for the coating of natural extracts, fatty oils and substances with bad taste and odor. It is a combination of natural shellac with plasticizers, coloring additives and additional excipients. It is a homogeneous, dry-milled, powdered compound, developed for the coating of all kinds of solid dosage forms. Natural shellac is a film forming polymer, which gives enteric properties for nutritional products. It is easily soluble in water and a reproducible high quality film coating can be achieved. Clear, white and colored preparations can be tailor-made according to customer requirements. If you are looking for a vegan formula we can use alginate sodium as a polymer.

BIOGRUND’s ready-to-use coloring agent TopMill® provides a homogeneous solid-color product. It is a unique, dry milled, homogeneous and deagglomerated blend of colors with additional excipients.

AquaPolish® STA has been developed for the fast coating of oral solid dosage forms. It is easily soluble and a reproducible high-quality film coating can be guaranteed. Due to its high solid content of 20–25% in the dispersion, a fast application at low process temperatures will improve your production process and save time. Additionally, your product gains a small barrier against moisture.

BIOGRUND’s one-step lubricant premix CompactCel® LUB enhances the flow of tablet production by reducing friction between particles at the interface between the tablet and the die wall. The lubricant reduces wear on punches and prevents sticking to punch faces. Furthermore CompactCel® LUB is also suitable for filling and closing hard gelatin capsules to achieve a smooth filling process.

BIOGRUND’s ready-to-use sugarcoating system IsuPolish® G is a unique, dry milled, homogeneous blend of isomalt mixed with mineral, non-artificial Candurin® pearl effect colors and additional excipients. The use leads to lustrous effects on sugar-coated tablets, granules, chewing gums, nuts and fruits. It also offers sophisticated solutions for brand enhancement and product refinement.

The ingredient premix CompactCel® MAB provides an oil and moisture holding capacity and prevents clumping of your powder blend. The homogeneous dry powder product controls humidity related issues in formulas or absorbs oily substances into free flowing powder.

AquaPolish G has been developed for the coating of all kinds of solid dosage forms. It is easily soluble and a reproducible high-quality film coating can be guaranteed. The widely approved, mineral colors of Candurin® are based on natural silicate combined with titanium dioxide and/or iron oxide.

BIOGRUND’s one-step film coating system AquaPolish® provides a protective and fast release film on tablets, pellets, granules and capsules. It is a unique, dry milled, homogeneous blend of selected film-forming cellulose ethers with plasticizing and coloring additives.

BIOGRUND’s one-step film coating system AquaPolish® E provides a protective film with excellent enteric properties. And with its superior light, oxygen and moisture protection, it is recommended for tablets, pellets, capsules and granules.

AquaPolish® PRO is a dry milled powdered compound is a ready-to-use film coating system that provides moisture sealing properties and a highly flexible film on solid oral dosage forms for immediate release profiles.

AquaPolish® TC is a combination of HPMC, HPC and other cellulose ethers with taste masking additives. Due to the further additives, which form a hardly soluble film, a tastemasking is achieved.

BIOGRUND’s ready-to-use coloring agent TopMill® G provides a homogeneous solid-colored product. It is a unique, dry milled, homogeneous blend of Candurin® pearl effect colors with additional excipients. The widely approved mineral colors are based on natural silicate combined with titanium dioxide and/or iron oxide and give your tablets a brilliant and unique appearance.

BIOGRUND’s sugar-coating system IsuPolish® provides a sugar-free dragée which has a pure and natural taste. It is suitable for diabetics (because of its low glycemic and low insulinemic response) and its cario-static properties.

AquaPolish® SR creates a strong and insoluble film coating with good adhesion, through which the active ingredient diffuses. The use of highquality, insoluble cellulose ethers or Ammonio Methacrylate Copolymer (Type A, Type B) in combination with soluble cellulose ethers, plasticizing and coloring additives, guarantees film coatings that are always reproducible. By varying the type and amount of the cellulose ethers used, a wide range of release profiles can be achieved.

BIOGRUND’s one-step binding agent CompactCel® provides an easy to use, granulated and homogeneous compound of PVP/NaCMC or HPC/ NaCMC, which acts as a perfect dry binder.

BIOGRUND’s sugar-coating system IsuPolish® S provides a sugar dragée with excellent taste and odor masking properties. Furthermore the dragée gets a smooth and glossy appearance.

The dry powder compound BonuTab® contains fillers, binders, disintegrant, lubricants and – if required – pigments for coloring issues. According to customer needs and depending on active pharmaceutical ingredients (API) the components of the premix can be individually adapted. An optimization of the tablet formulation can be done. Preparation of the complete tablet mass in just one step by blending BonuTab® with the API.

IsuPolish® FSC is a unique, dry milled, homogeneous blend of hypromellose, Isomalt or sucrose, pigments and additional excipients. Compared to a traditional sugar-coating process this product assists you to speed up the production process.

BonuCel® provides easy-to-use cellulose ethers for pharmaceutical and nutritional products. The main application of Hypromellose is film coating. The fine, homogeneous blends of selected high quality cellulose ether polymers provide excellent film forming properties and sustained release profiles. A wide range of standard viscosities is offered to deal with different application requirements. Additionally, BIOGRUND offers an exclusive service by finely adjusting viscosities.

BIOGRUND provides a wide range of ready-to-use film coating products which includes AquaPolish® MS. It's a moisture sealing product. It provides a protective and fast soluble film on tablets, pellets, granules and capsules. It is a combination of selected film-forming cellulose ethers with plasticizing and coloring additives. The use of hydrophobic excipients gives excellent protection against moisture. The product is designed to improve the coating process and can be applied using conventional or modern coating equipment. It is a homogeneous, dry-milled, powdered compound, developed for the coating of all kinds of solid dosage forms. It is easily soluble and a reproducible high-quality film coating can be achieved. Clear, white and colored preparations can be tailor-made according to customer requirements. Contact us for more information.

CompactCel® FLO is a flow agent for loosening powder mixtures and improving flowability. The ready-touse powder compound replaces synthetic additives such as silicon dioxide. It prevents bridge formation during flow from hopper and provides a clean funnel flow of the powder mass to be processed during both tableting and capsule filling.

BIOGRUND’s one-step film coating system AquaPolish® OM perfectly masks bad and strong smelling actives (e. g. herbal extracts). Sealing these characteristics by using AquaPolish® OM enables a pleasant application for the consumer and increases patient compliance. It provides a protective and economical coating on tablets, pellets, granules and capsules without influencing the disintegration time.

Biogrund's ready-to-use excipient premix BonuWax® for hot melt coating is a water and solvent free application and provides good moisture sealing, taste masking and stability for granules and particles. BonuWax®, consisting of carnauba and/or beeswax plus two additional lipids, has a suitable melting temperature and is easy to apply on particles and granules by a fluid bed coating process. BonuWax® can be sprayed with a 100% solid content which leads to a high productivity.

BonuTone® is a ready-to-use master batch, developed for the coloring of all kinds of creams, sugar-coating dispersions and chewing gums. It can be used in liquids in a simple and easy way.

CompactCel® DIS is a natural/organic super-disintegrant which enables a rapid break-up of solid dosage forms when they come into contact with moisture. The super-disintegrant premix is formulated with natrual ingredients which complies with current Clean Label Standards. It provides an alternative to synthetic super-disintegrants, such as crosslinked polymers, crosscarmellose sodium or sodium starch glycolate. CompactCel® DIS helps in the fast breakdown of the solid dosage form so that the active ingredient becomes bioavailable faster and is readily absorbed. It can be also used in the formulation of oral disintegrating tablets (ODT) or chewing tablets.

BIOGRUND’s one-step matrix agent CompactCel® SR provides an easy-to-use compound which controls the sustained release of active ingredients. CompactCel® SR forms a gel, through which the active ingredient diffuses. The use of NaCMC accelerates the gel-forming process, so the initial drug release is reduced.

AquaPolish® C has been developed to improve running production processes. Furthermore, it is an ideal basis for researching new solutions. The contract manufactured compound is a unique, dry milled, homogeneous blend of film coating polymers, plasticizing and coloring additives and other excipients. It can be applied by using conventional or modern coating equipment.

BIOGRUND’s one-step film coating system AquaPolish® PVA provides a protective and fast soluble film on tablets, pellets, granules and capsules. It is a unique, dry milled, homogeneous blend of selected filmforming polymers with coloring and a few plasticizing additives. AquaPolish® PVA is a combination of polyvinyl alcohol and optional HPC, which gives excellent moisture sealing by using aqueous solvent applications.

Simple Solvents 200 Proof USP grade anhydrous ethyl alcohol is amongst the highest purity ethanol available on the market. Ethanol is an ideal solvent for botanical processing including medicinal hemp & cannabis, terpenes, pectin, and more. USP grade ethanol from Simple Solvents has been tested meeting pharmaceutical standards.

We obtain our human plasma exosomes using plasma from healthy human donorsVerified free from major human viruses including HIV, HBC, and HCVExosomes offer many of the same therapeutic benefits as living cells without the safety concerns associated with live-cell injectionNanoparticle encapsulation of a drug can improve drug solubility, stability, and half-lifeExosomes can be loaded with a variety of drugs, proteins, nucleic acids, etc. for a wide variety of treatment goalsExosomes also naturally contain valuable biological materials such as lipids, nucleic acids, growth factors, enzymes, and proteins

Strahl & Pitsch, LLC is the leading global refiner of Beeswax, producing White and Yellow Grades of Beeswax, certified to the current USP/NF Monograph, Food Chemicals Codex, and other compendium.The company sources crude wax from dozens of countries throughout the world. Our valued supplier relations are personal, trusted and long term associations. Among our wax sources we count individual beekeepers, local co-operatives, fair-trade community groups, honey industry suppliers and established and reliable international traders.

USI Chemical USi-PDMS 12500 is a special product which has excellent physical and chemical properties.

Headcel® HPMC 75HD4000 is mid-viscosity Hydroxypropyl Methyl Cellulose (HPMC) which is designed for using in a wide range of pharmaceutical applications.

Immediate release colorless pre-coating system.