Knowde Enhanced TDS
Identification & Functionality
- INCI Name
- Cosmetic Ingredients Functions
- CAS No.
- 55406-53-6
- EC No.
- 259-627-5
- Technologies
- Product Families
- Compositional Breakdown
INCI Designation Cas No. EINECS No. 3-Iodo-2-propynylbutylcarbamate 55406-53-6 259-627-5 PEG-4 laurate 9004-81-3 618-396-4 PEG-4 dilaurate 9005-02-1 618-406-7 Polyethylene glycol 25322-68-3 500-038-2 Ingredient Composition % 3-Iodo-2-propynylbutylcarbamate 9.1-10.3% Polyethylene glycol cocoate 39-41% Polyethylene glycol dicocoate 39-40% Polyethylene glycol 9.1-10.3%
Features & Benefits
- Benefit Claims
- Labeling Claims
- Key Attributes
- Highly effective fungicide; remarkably efficient in inhibiting growth of yeast and mold
- Has a wide range of global regulatory approvals
- Temperature stable
- Compatible with commonly used ingredients such as cationic, anionic, nonionic surfactants, emulsifiers and proteins
- Low use levels for efficacy
- Convenient liquid form provides easier handling
Applications & Uses
- Markets
- Applications
- AP/Deo Applications
- Bath & Shower Applications
- Color Cosmetic Applications
- Hair Care Applications
- Personal Hygiene Applications
- Skin Care Applications
- Sun Care Applications
- Wipes, Tissue & Towel Applications
- Use Level
- 0.03–0.5%
- Application pH Range
- 2–9
- Applications
- Anhydrous
- Baby care (rinse-off only)
- Body wash
- Conditioner
- Cream
- Deo / Anti-perspirant
- Eye creams/gels
- Eye shadow
- Face lotion
- Face wipes
- Facial cream
- Foundation
- Hair gel
- Hand soap
- Lotion
- Make up remover
- Mascara
- Oil in Water
- Powder
- Shampoo
- Toner
- Water in Oil
- Formulation Recommendations
- Readily soluble in the presence of water and a polar organic compound
- Can also be pre-solubilized in the surfactant component
- Should be added below temperatures of 40˚C
- It can be pre-solubilized in a combination of water and polar organic component
- Some of the commonly used polar organic compounds are as follows:
1. Anionic surfactants
2. Nonionic surfactants
3. Cationic surfactants
4. Alcohols
5. Glycols
6. Glycol Ethers - Can be used between pH 2–10, although end user should confirm the stability and efficacy in each specific system
- Can be inactivated by strong reducing agents, acids and bases
- Typically needs to be used in combination with a bactericide
- DMDMH (Glydant® products), phenoxyethanol, CMI/MI (Isocil® products) or other bactericide can be used
- Formulator to confirm that there are no patent issues
Properties
- Physical Form
- Odor
- Characteristic
- Soluble in
- Oil
Regulatory & Compliance
- Certifications & Compliance
- Chemical Inventories
- Global Regulatory
Europe
- Approved under Annex V to Regulation EC/1223/2009
- Allowed in rinse-off products up to 0.02% IPBC and up to 0.01% IPBC in leave-on products except in creams and lotions aimed to be applied on a large part of the body
- Allowed for use in antiperspirants/deodorants up to 0.0075% IPBC
- Not allowed for oral hygiene and lip products or in preparations for children under the age of 3 except in rinse-off applications
Japan
- Listed in the positive list. Can be used at a level up to 0.02% IPBC in leave-on and rinse-off products
United States
- Approved by CTFA for both rinse-off and leave-on applications.
Maximum use level of 0.1% for IPBC
Technical Details & Test Data
- Efficacy Shampoo
Microbiological Challenge Studies
Studies were run using various concentrations of Glycacil® L in various formulations to see efficacy on a mixed inoculum of fungi. All samples were inoculated at the beginning of the study, sampled at 24 hours, 3, 7, 14, 21 and 28 days.Log count and % reduction : Shampoo at 0.03% Glycacil® L Organism 0 Day 2 Day 7 Day 14 Day 21 Day 28 Day C. albicans 10^5 10^4 10^3 <10 <10 <10 % Reduction - 95.08 97.54 >99.99 >99.99 >99.99 A. brasiliensis 10^5 10^5 <10 <10 <10 <10 % Reduction - 61.90 >99.99 >99.99 >99.99 >99.99 - Shampoo Formula
Shampoo– pH7.0
Ingredient Description Supplier % Marlinat 242/70 SLES 2EO 70% Sasol 17.14 Dehyyton K CAPB 30% BASF 6.67 NaCl - Fisher 1.0 Deionised water - - 75.19
Packaging & Availability
- Country Availability
- Regional Availability