company tower banner
Arxada Company Logo

Proxel® MB4 Preservative

1 of 25 products in this brand
Proxel® MB4 Preservative is a solvent-free, zero VOC, broad spectrum preservative for the protection of industrial water-based products against spoilage from bacteria, yeasts and fungi. It is a dual active blend of 1,2-benzisothiazolin-3-one (BIT) and 2-methyl-4-isothiazolin-3-one (MIT) that has been specially formulated. The actual labeling requirements for the formulated product should however be discussed with your local Lonza representative.

Functions: Anti-Microbial Agent, Preservative

Chemical Family: Isothiazolinones

Certifications & Compliance: ISO 9001

    Knowde Enhanced TDS

    Identification & Functionality

    Chemical Family
    CASE Ingredients Functions
    Cleaning Ingredients Functions
    Chemical Structure

    Proxel® MB4 Preservative - Chemical Structure

    Composition

    An aqueous solution of 1,2-benzisothiazolin-3-one (BIT) and 2-methyl-4-isothiazolin-3-one (MIT)

    Features & Benefits

    Applications & Uses

    Applications

    The product is effective in polymer emulsions, paints, adhesives, pigment dispersions and household products.

    Amount to Use

    The concentration required to adequately preserve your product depends on several factors. These include the susceptibility of the system to microbiological degradation, the extent to which microorganisms can gain access, the species involved, pH, temperature, and length of time for which protection is required.

    Results of initial studies indicate that a concentration of PROXEL™ MB4 Preservative in the range 0.1-0.3% should be sufficient for most applications. Since the effective concentration can be dependent on several factors it is recommended that a testing program can be undertaken to determine the most cost-effective dose for your application.

    Testing should take into account chemical compatibility/stability, plant hygiene conditions, susceptibility of the product to contamination, and the typical organisms involved.

    Properties

    Physical Form
    Typical Physical Properties
    ValueUnitsTest Method / Conditions
    pH Value (25°C)8.0 - 9.5
    Boiling Point100°C
    Flash PointBoils without flashing
    Density (at 25°C)1.02 - 1.03g/ml
    Minimum Inhibitory Concentrations (MIC)

    Table 1.

    Micro-organism MIC (ppm)
    Bacteria  
    Alcaligenes faecalis IMI 358536 15
    Bacillus subtilis NCTC 10400 40
    Burkholderia cepacia NCIMB 13694 190
    Enterobacter cloacae CIP 104674 470
    Escherichia coli IMI 362054 220
    Proteus vulgaris IMI 358534 110
    Pseudomonas aeruginosa IMI 358539 435
    Pseudomonas putida IMI 358533 310
    Pseudomonas stutzeri NCIMB 11359 55
    Staphylococcus aureus NCIMB 9518 80
    Fungi  
    Aureobasidium pullulans PRA FS/1 220
    Cladosporium herbarum PRA FS/5 150
    Yeasts  
    Rhodotorula rubra NCTC 9449 440
    Saccharomyces cerevisiae NCYC 87 875
    Preservative Properties

    This product is effective against a range of problem microorganisms some of which are listed in Table 1. Please note that Minimum Inhibitory Concentrations (MIC) do not represent effective in-use concentrations which should be discussed with your local Lonza representative.


    PROXEL™ MB4 Preservative has a non-specific mode of action which means
    that bacterial resistance is very unlikely to occur.

    Compatibility

    Avoid strong alkaline conditions, oxidizing agents, reducing agents, amimes and mercaptans

    Regulatory & Compliance

    Certifications & Compliance
    Total Quality

    Lonza holds a number of ISO 9001 Quality Management registrations covering our product range. The scope of each registration is specific to the location or entity named on the Registration Certificate and our products are supplied to ISO 9001 Standards.

    Regulatory Information

    The components of PROXEL™ MB4 Preservative are in compliance with the following inventories:

    • EINECS (Europe)
    • TSCA (USA)
    • AICS (Australia)
    • ENCS (Japan)
    • DSL (Canada)
    • KECL (Korea)
    • PICCS (Philippines)
    • IECSC (China)

    Safety & Health

    Risk Assessment and Management

    Lonza professionals have a wide expertise in the fields of Safety, Health and the Environment. Lonza Microbial Control is committed to and uses this expertise in understanding the suitability of PROXEL™ MB4 Preservative for specific applications

    Health and Safety

    The PROXEL™ MB4 Preservative Safety Data Sheet may be supplied upon request. It should be read and understood by all supervisory personnel and employees before using this product

    Packaging & Availability

    Country Availability
    Regional Availability
    • Africa
    • China
    • Europe
    • India
    • Japan
    • Latin America
    • Middle East
    • North America
    • Oceania
    • South East Asia

    Storage & Handling

    Storage & Stability

    Stable under normal conditions of storage down to 0°C. If frozen, allow to thaw and stir well before use.