Kolliphor® P 188 Micro Geismar

Identification & Functionality

Chemical Name

Poloxamer 188

Country of Origin

United States of America (USA)

Ingredient Origin

Non-Animal Origin,

Synthetic

Pharma & Nutraceuticals Functions

Dispersant,

Emulsifier,

Gelling Agent,

Lubricant,

Plasticizer,

Solubilizer,

Wetting Agent

Technologies

Pharmaceuticals & Nutraceuticals

Product Families

Pharmaceuticals & Nutraceuticals — Excipients

Base Fluids, Glidants & Lubricants,

Emulsifiers & Stabilizers,

Formulation & Processing Aids,

Solvents & Solubilizers

Features & Benefits

Labeling Claims

Aflatoxin-free,

Allergen-free,

BSE-free,

Contamination-free,

Dioxin-free,

Gluten-free,

Halal,

Kosher,

Latex-free,

Melamine-free,

Non-GMO,

Not Engineered With Nanomaterials,

Phthalates-free,

Sustainable,

TSE-free

Key Benefits

• Microprilled poloxamers were microprilled to an average particle size of approximately 50 µm
• Dissolution enhancer for actives in tablets and capsules
• Lubricant for actives incompatible with Mg-stearate, e.g. ibuprofen
• Polishing agent for film-coated tablets
• Dispersing/wetting agent
• Water soluble lubricant, e.g. for effervescent tablets
• Supports lubrication needs in direct compression and dry granulation production of tablets and capsules

Applications & Uses

Markets

Healthcare & Pharma

Applications

Healthcare & Pharma — Drug Delivery & Care Solutions

Oral,

Parenteral,

Topical,

Transdermal

Dosage Form

Creams,

Dispersions,

Emulsions,

Foams,

Gels,

Injectables,

Soft Gels,

Transdermal Patches

Manufacturing Technology

Capsule Filling,

Direct Compression,

Dry Granulation,

Hot Melt Extrusion,

Melt Granulation,

Spray Drying

Properties

Physical Form

Beads,

Capsules,

Powder,

Solid,

Tablets

Appearance

White to slightly yellowish microbeads

Soluble in

Water, ethanol, polar solvents

Insoluble in

Ether, paraffin, fatty oils

Particle Size Distribution

	Value	Units	Test Method / Conditions
Particle Size	approx. 50	µm	—

Regulatory & Compliance

Certifications & Compliance

DMF Type IV,

ECOVADIS,

European Pharmacopeia (Ph. Eur.),

FDA Compliant,

ISO 9001,

International Standards For Phytosanitary Measures No. 15 (ISPM 15) Compliant,

OHSAS,

REACH Exempt (Europe),

United States Pharmacopeia (USP),

cGMP

Chemical Inventories

TSCA Exempt (USA)

Grade

Pharma Grade

Packaging & Availability

Packaging Type

Drums

Packaging Information

• 0.5KG Plastic bottle (Sample)
• 25KG Fiber drums

Storage & Handling

Storage Information & Retest Period

• Store below 30°C. Store in tightly closed containers.
• Retest Period : 36 months