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DermalRx® LuShield™ (R10056)

1 of 8 products in this brand
DermalRx® LuShield™ (R10056) is a proprietary extract of the fragrant flowering Osmanthus fragrans shrub that delivers anti-aging effects through senolytic, antioxidant, anti-inflammatory, and protective activities. DermalRx® LuShield™ addresses cellular senescence due to environmental and dietary stressors while also protecting collagen and the extracellular matrix (ECM, the structural foundation of the skin) from the damaging effects of advanced glycation end-products (AGEs), UV radiation, free radicals, and pollution (PM2.5). DermalRx® LuShield™ protects the skin to facilitate the natural repair, rebuilding, and restructuring of skin and skin matrices for a healthy and youthful appearance.  

INCI Name: Osmanthus Fragrans Flower Extract

Ingredient Origin: Natural Origin, Plant Origin

Functions: Anti-Aging Agent

Labeling Claims: Gluten-free, Natural, Naturally Derived, Non-Irritant, Not Tested on Animals, Plant-Based, Sustainable, Vegan

Benefit Claims: Anti-Aging, Anti-Glycation, Anti-Pollution, Antioxidant Properties, Calming, Compatibility, Excellent Stability, Free Radical Scavenging, High Bioavailability, Highly Restructuring, Improves Cell Longevity, Promotes Youthful Skin, Protection From Environmental Damage, Repairing, Senescence Prevention, Skin Protection, Soothing, Stress Reducing, Suitable for Sensitive Skin, UV Protection

Certifications & Compliance: California Proposition 65

Knowde Enhanced TDS

Identification & Functionality

Cosmetic Ingredients Functions
Origin
DermalRx® LuShield™ is produced from Osmanthus fragrans via a proprietary extraction method that yields an extract with maximal bioactivity and bioavailability to the skin.

Features & Benefits

Benefits & Claims
  • Botanical derived active produced from Osmanthus fragrans (Asian Tea Olive) flowers via proprietary extraction
  • Contains high concentrations of active polyphenols that provide strong antioxidant activity against environmental stress
  • Inhibits the inflammatory effects of urban air pollution
  • Inhibits glycation of skin proteins and other important bio-molecules
  • Induces the expression of four types of collagen, as well as seven genes important for cell-ECM and cell-cell interactions
  • Protects dermal cells (fibroblasts) from AGE-induced toxicity
  • Helps to reverse senescent change in mature fibroblasts to a decades-younger phenotype
  • Excellent stability for long-lasting antioxidant/anti-inflammatory efficacy

Applications & Uses

Application Format
Skin Care Applications
Sun Care Applications
Use Level
1 - 3%
Applications
  • Skin care products targeting skin protection and aging prevention
  • Anti-aging regimes targeting oxidative and glycation-induced damage (caused by pollution, UV radiation, etc.)
  • Longevity boosting skin care formulas for mature consumers
  • Topical products for diabetic skin and/or for consumers with dietary-related disorders (high circulating glucose levels)
  • Day creams and pre- and post- sun care formulas
  • Soothing and calming for sensitive skin
Compatibility and Formulation
DermalRx® LuShield™ is water-miscible and is compatible with conventional ingredients used in skin care products. Add to product at temperatures below 50°C. As seen in the below photograph, DermalRx® LuShield™ has minimal effect on the color of base creams.

Properties

Physical Form

Regulatory & Compliance

Certifications & Compliance
Regulatory Information
  • This product has not been tested on animals, and our company adheres to the written provisions of such animal rights organizations as Leaping Bunny and Cruelty/Free International.
  • This product contains no animal products. It is manufactured using only plant based or synthetically derived (non-animal origin) materials and is thereby declared a Vegan Product.
  • All materials used to produce this product are procured using sustainable sourcing practices.
  • This product is manufactured in accordance with the current Good Manufacturing Practices (cGMP) requirements established by the U.S. Food and Drug Administration (FDA) for cosmetics. Furthermore, Biocogent, LLC, and this production facility(ies), are registered as cosmetic manufactures with the FDA.
  • REACH compliance: All of the ingredients (substances) used in the manufacture of this product (mixture)are either registered under REACH, or qualify for an Article 2 (low volume of less than 1 metric ton), Annex IV or Annex V exemption, making our product REACH compliant.
  • Proposition 65 compliance: Based upon Biocogent LLC’s knowledge of our business operations and chemical formulations, no chemicals listed by the State of California Environmental Protection Agency are used in our products, or as a processing aid for any product manufactured in our facility.

Technical Details & Test Data

Test Data

Inhibition of AGE Formation

Safety & Health

Safety
Human Repeat Insult Patch Testing (HRIPT) under semi-occlusive conditions indicated that DermalRx® LuShield™ did not perform as a primary skin irritant or as a primary skin sensitizer at recommended use levels. Ocular Irritection testing predicted that DermalRx® LuShield™ would be a Minimal ocular irritant at recommended use levels.

Storage & Handling

Shelf Life
18 Months
Storage Condition
DermalRx® LuShield™ should be stored at room temperature in original packaging away from heat and light.