Products

Tellirictin® (R10047) is a proprietary clove flower extract containing natural gallate-based pleiotropic compounds (tellimagrandin I and casuarictin) for multi-functional anti-aging performance. Tellirictin® addresses the many signs of aging by delivering brightening, anti-wrinkle, and moisturizing activities, while also protecting the skin from oxidative, inflammatory, proteolytic, and environmental stresses. Applications of Tellirictin® include anti-aging, anti-wrinkle, and skin-brightening regimens, soothing and calming products for sensitive skin, and pre- and post-sun care.   Tellirictin® prevents excessive melanin production to combat hyperpigmentation by inhibiting tyrosinase activity as efficiently as beta-arbutin. Tellirictin® protects collagen and other components of the extracellular matrix (ECM, the structural foundation of the skin) from damaging enzymes (MMPs and elastases) associated with environmental stressors such as environmental pollution and UV (sun) exposure. Tellirictin® modulates microRNAs involved in the beneficial regulation of DNA repair, barrier protection, and anti-inflammatory pathways. 

Pleiotanicals® Ellagicin®(R10068) is a botanically derived active ingredient containing proprietary acai and pomegranate “superfruit” extracts for antioxidant and anti-aging benefits. Ellagicin® is rich in ellagic acid, anthocyanins, and other natural antioxidants that provide protection from oxidative and proteolytic stress. Ellagicin® protects collagen and other components of the extracellular matrix (ECM, the structural foundation of the skin) from damaging enzymes associated with environmental stressors such as environmental pollution and UV (sun) exposure. Applications of Ellagicin® include anti-aging and anti-wrinkle regimens, soothing and calming products for sensitive skin, and pre- and post-sun care.

Pleiotanicals® Scavenox® GTE (R10025) is a highly stable green tea extract with epigallocatechin gallate (EGCG) for long-term antioxidant, anti-inflammatory, and skin-brightening activity. Applications for Scavenox® GTE include anti-aging and anti-blemish regimens, skin-brightening and skin tone-balancing systems, and soothing and calming products for sensitive skin.   Scavenox® GTE protects the skin from oxidative stress with the demonstrated ability to prevent UV-induced lipid peroxidation and scavenging of singlet oxygen. Scavenox® GTE also inhibits inflammatory and proteolytic (MMPs and elastase) damage for protection against UV radiation, pollution, and other environmental stressors. These activities offer skin protection and renewal by preserving collagen and other components of the extracellular matrix (ECM, the structural foundation of the skin). Scavenox® GTE prevents excessive melanin production to combat hyperpigmentation by inhibiting tyrosinase activity.

HEDI® Mango Butter (R10076) is a unique water-based dispersion of mango butter with babassu oil, squalane, and vitamin E in a silicone-free microdispersion carrying more than 30% hydrophobe. HEDI® Mango Butter is a plant-derived alternative for paraffin and silicone-based emollients. Applications for HEDI® Mango Butter include moisturizing treatments for very dry, rough, and cracked skin, skincare products for sensitive skin, and skin, scalp, and hair care conditioning formulas. A soft solid with a very slight sweet scent, Mango Butter exhibits excellent moisturizing properties and good lubricity. Mango Butter, obtained from de-shelled fruit kernels of the mango tree, has natural antioxidant, anti-inflammatory, and antimicrobial properties. Organic certified babassu oil is extracted from wild-picked fruits of the babassu palm tree, offering softening properties with glycerides of lauric, myristic, and oleic acids. HEDI® products are stable ingredient blends of aqueous and oil-based materials made using a unique manufacturing process. HEDI® products are ultra-concentrated homogeneous constructs that are infinitely dilutable in aqueous systems. HEDI® products have superior aesthetics while simplifying formulation and manufacturing processes and enhancing the delivery of active ingredients in the formula. HEDI® products can be adjusted to achieve a consistency that is milk-like (pourable and even sprayable), creamy, or paste-like. Tactile properties can be light and silky or velvety and more occlusive. HEDI® products streamline manufacturing processes for time, energy, and cost savings by avoiding additional heating, melting, and mixing steps. HEDI® products are amenable to cold processes and do not require surfactants or emulsifiers.HEDI® products have properties similar to the skin barrier, promoting skin permeability and facilitating delivery through the lipid-rich, waterproof stratum corneum. Finished products have a better feel and provide superior surface coverage when compared to traditionally formulated butters and oils.

HEDI® Avocado (R10089) is a unique combination of avocado butter with plant-derived squalane, radish seed extract, and vitamin E in a silicone-free microdispersion carrying more than 30% hydrophobe. Avocado Butter is an occlusive moisturizer to lock in moisture, rich in essential fatty acids and antioxidants. Squalane and radish seed extract act as emollients to help to soothe and soften, and improve skin barrier function. Vitamin E shields from oxidation and free radicals. Applications for HEDI® Avocado include moisturizing treatments for very dry, rough, and cracked skin, skincare products for sensitive skin, and skin, scalp, and hair care conditioning formulas.HEDI® products are stable ingredient blends of aqueous and oil-based materials made using a unique manufacturing process. HEDI® products are ultra-concentrated homogeneous constructs that are infinitely dilutable in aqueous systems. HEDI® products have superior aesthetics while simplifying formulation and manufacturing processes and enhancing the delivery of active ingredients in the formula. HEDI® products can be adjusted to achieve a consistency that is milk-like (pourable and even sprayable), creamy, or paste-like. Tactile properties can be light and silky or velvety and more occlusive. HEDI® products streamline manufacturing processes for time, energy, and cost savings by avoiding additional heating, melting, and mixing steps. HEDI® products are amenable to cold processes and do not require surfactants or emulsifiers.HEDI® products have properties similar to the skin barrier, promoting skin permeability and facilitating delivery through the lipid-rich, waterproof stratum corneum. Finished products have a better feel and provide superior surface coverage when compared to traditionally formulated butters and oils.

Pleiotanicals® Holy Basil OSP (R10110) is a proprietary extract of Ocimum sanctum (a plant used in Ayurvedic medicine) for pollution protection and aging prevention in the skin. Holy Basil OSP contains key active molecules, including polyphenols and pentacyclic triterpenoids, that protect against environmental pollution with anti-aging benefits. Holy Basil OSP is ideal for anti-aging, anti-wrinkle, de-stressing, and pollution/UV protection regimens, as well as soothing, calming products for sensitive skin.   Holy Basil OSP reduces a suite of inflammatory mediators in the skin typically induced by exposure to airborne particular matter (PM2.5). Holy Basil OSP protects the extracellular matrix (ECM, the structural foundation of the skin) against damaging oxidative, proteolytic, and inflammatory stress while also modulating collagen and other genes fundamental for ECM structure and integrity.

DermalRx® LuShield™ (R10056) is a proprietary extract of the fragrant flowering Osmanthus fragrans shrub that delivers anti-aging effects through senolytic, antioxidant, anti-inflammatory, and protective activities. DermalRx® LuShield™ addresses cellular senescence due to environmental and dietary stressors while also protecting collagen and the extracellular matrix (ECM, the structural foundation of the skin) from the damaging effects of advanced glycation end-products (AGEs), UV radiation, free radicals, and pollution (PM2.5). DermalRx® LuShield™ protects the skin to facilitate the natural repair, rebuilding, and restructuring of skin and skin matrices for a healthy and youthful appearance.  

Pleiotanicals® Holy Basil OSE (R10104) is a proprietary extract of Ocimum sanctum (a plant used in Ayurvedic medicine) for pollution protection and aging prevention in the skin. Holy Basil OSE contains key active molecules, including polyphenols and pentacyclic triterpenoids, that protect against environmental pollution with anti-aging benefits. Holy Basil OSE is ideal for anti-aging, anti-wrinkle, de-stressing, and pollution/UV protection regimens, as well as soothing, calming products for sensitive skin.   Holy Basil OSE reduces a suite of inflammatory mediators in the skin typically induced by exposure to airborne particular matter (PM2.5). Holy Basil OSE protects the extracellular matrix (ECM, the structural foundation of the skin) against damaging oxidative, proteolytic, and inflammatory stress while also modulating collagen and other genes fundamental for ECM structure and integrity.

DermalRx® CKW (R10091) is a plant-derived combinatorial curcuminoid extract that potently and dose-dependently modulates excess sebum production by inhibiting type I and type II 5α-reductase. Clinical evaluation showed significant reductions in sebum production and a visible decrease in facial sheen. DermalRx® CKW is ideal for sebum-regulating products for skin and hair applications, as well as anti-blemish and pore-minimizing formulations.

DermalRx® Acetygen® (R10117) is a botanical active ingredient featuring Agrimonia eupatoria and Ampelopsis grossedentata extract with potent phytochemicals (including dihydromyricetin, myricetin, and other bioactive flavonoids). DermalRx® Acetygen® is a potent senolytic and broad-spectrum epigenetic modulator for applications in skin health and wellness, such as anti-aging products targeting oxidative, environmental, and inflammatory damage. DermalRx® Acetygen® enhances natural skin repair mechanisms to help eliminate dysfunctional senescent cells that contribute to signs of tissue aging. By regulating the histone deacetylase (HAT/HDAC) “switch”, DermalRx® Acetygen® epigenetically restores gene expression to levels found in younger skin for a renewed extracellular matrix (ECM). DermalRx® Acetygen® protects the skin from oxidative stress and inflammatory damage while rejuvenating the tissue for a youthful, healthy appearance. 

DermalRx® FSE (R10111) is a marine bioferment produced from Sargassum vulgare for DNA protection and repair in sun-exposed skin. Rich in bioactive phlorotannins, DermalRx® FSE stimulates the skin’s natural DNA repair process through nucleotide excision repair (NER). Ex vivo studies demonstrate DermalRx® FSE’s DNA protective and reparative effects after UV exposure. DermalRx® FSE also provides strong anti-pollution activity, protecting the skin from damaging oxidation and inflammation. DermalRx® FSE is ideal for anti-aging, de-stressing, soothing and calming, and pre- and post-sun care products.

Pleiotanicals® Scavenox® HH (R10109) is a highly stable green tea extract with epigallocatechin gallate (EGCG) for long-term antioxidant, anti-inflammatory, and skin-brightening activity. Applications for Scavenox® HH include anti-aging and anti-blemish regimens, skin-brightening and skin tone-balancing systems, and soothing and calming products for sensitive skin. Scavenox® HH protects the skin from oxidative stress with the demonstrated ability to prevent UV-induced lipid peroxidation and scavenging of singlet oxygen. Scavenox® HH also inhibits inflammatory and proteolytic (MMPs and elastase) damage for protection against UV radiation, pollution, and other environmental stressors. These activities offer skin protection and renewal by preserving collagen and other components of the extracellular matrix (ECM, the structural foundation of the skin). Scavenox® HH prevents excessive melanin production to combat hyperpigmentation by inhibiting tyrosinase activity.

Grandiciin® (R10124) is an Epimedium extract featuring a beneficial mix of prenylated flavonoids for addressing blemished skin. Applications for Grandiciin® include microbiome-balancing products, anti-blemish and spot treatments, anti-sebum and oil-reducing hair and skin care, and soothing and calming body care regimens for damaged skin. Grandiciin® improves skin health and wellness through microbiome-rebalancing activity, reducing the problematic Cutibacterium acnes (formerly Propionibacterium acnes) biofilms that contribute to inflammation, redness, and blemish formation. Grandiciin® is clinically shown to diminish C. acnes burden on the skin while also reducing sebum (oil) production and signs of inflammation and redness and improving the appearance of blemishes in four weeks. Grandiciin® addresses inflammatory, proteolytic, and oxidative stress to provide an extra layer of protection against tissue damage and scarring in severely blemished skin.