Products in Pharmaceutical Manufacturing: Stabilizer

NEOSORB® BioPharma Low endotoxin grade sorbitol provides protein stabilization in your biopharmaceutical downstream applications. Known for its high water solubility, it is a proven formulation aid for biopharmaceuticals. Sorbitol is used as an excipient in over 35 commercial mAbs, therapeutic proteins and vaccines. Roquette's in process quality controls ensure a consistent supply of raw materials and excipients to help bring your biologics to life. Through our integrated supply chain and rigorous quality systems, we reduce the risks associated in biopharmaceutical manufacturing. NEOSORB® BioPharma is suitable for use in biopharmaceutical manufacturing and as an excipient for injectable dosage forms. Contact us today to talk about our multi-compendial materials - EP, JP, and USP.

KLEPTOSE® LINECAPS Pea Maltodextrin Cyclodextrin can be used as a solubilizer, stabilizer and taste-making agent in pharma oral dosage applications. Applications Swallowable, chewable and effervescent tablets Lozenges Hard and soft capsules Orally dissolving films Blends Granules Pellets premix Medicated confectionery Syrups Suspensions Liquids Cream Paste Semi-solids

BTC Europe GmbH 1,4-Dioxan stab. ultra-pure, classified within the heterocyclic compounds chemical family. It serves various industries, including chemical manufacturing in the industrial sector, pharmaceutical manufacturing in healthcare, pharmaceuticals for API manufacturing, laboratory and research purposes, and pharmaceutical processing. This compound is integral to processes involving chemical production and pharmaceutical manufacturing.

BTC Europe GmbH 1,4-Dioxane stab. in liquid form, primarily serving as an API intermediate, solvent, and stabilizer. Its applications extend across the healthcare and pharmaceutical industries, specifically in pharmaceutical manufacturing for API manufacturing, laboratory and research purposes, and pharmaceutical processing.

Dissolvine NA2-P is a ethylenediaminetetraacetic acid (EDTA), disodium salt.

AllanChem Magnesium Chloride is an inorganic solid available as granules and crystals. This product is used as a firming agent, coagulant, and stabilizer. It is used in chemical manufacturing.

AllanChem Sodium Carbonate Anhydrous is a high-quality, inorganic, white or almost white, slightly granular, hygroscopic powder used as a stabilizer and acidity regulator. This product is used in chemical manufacturing.

AllanChem Microcrystalline Cellulose is a high-quality, free-flowing powder. This product is used as a stabilizer, viscosity modifier, opacifier, bulking agent, and absorbent.

AllanChem EDTA Disodium Salt DiHydrate is a high-quality, white crystalline powder used as a stabilizer.

AllanChem Potassium Phosphate Dibasic Anhydrous is a high-quality, inorganic, colorless or white-colored powder that is used as a stabilizer and acidity regulator. This product is used in the manufacturing of pharmaceuticals.

Sarda Gums and Chemicals Sarcol FT appears as transparent type that contains a stabilizer, a bulking agent, a thickener, a shelf life enhancer, a dough conditioner, a texturizing agent, a suspension aid, a viscosity modifier, an encapsulant, a glazing agent, a film former, a binder, and a lubricants.

Chemicals and Sarda Gums Sarcol FX is a high purity food grade that contains a stabilizer, a bulking agent, a thickener, a shelf life enhancer, a dough conditioner, a texturizing agent, a suspension aid, a viscosity modifier, an encapsulant, a glazing agent, a film former, a binder, and a lubricants.

CELNY SL is a water soluble, non-ionic derivative of cellulose, an abundant and natural polysaccharide found in all plants. CELNY™ brand is a high quality grade of HPC for food and nutraceutical use. CELNY is available in a wide range of viscosities and particle sizes to suit your application needs. It is food use approved globally, non-GMO, non-dairy, gluten and common allergen free. CELNY HPC applications include tablet binder, film forming agent, and stabilizer.

Iota Carrageenan that forms soft gels in the presence of calcium ions. It is produced mainly from Eucheuma denticulatum.

TEMCOL 30 is a Refined and very high viscosity, high performing.

Cyclolab (2-Hydroxypropyl)-gamma-cyclodextrin is a gamma cyclodextrin that is a derivative of an 8-membered sugar ring molecule. (2-Hydroxypropyl)-γ-cyclodextrin can crosslink to form longer polymers. This overall is a very useful chemical for supramolecular chemistry. (2-Hydroxypropyl)-γ-cyclodextrin is also used in the solubilization of macromolecules and in cell culture applications. (2-Hydroxypropyl)-γ-cyclodextrin is similar to β-Cyclodextrin (sc-204430), but (2-Hydroxypropyl)-γ-cyclodextrin can work with larger molecules.

Luctoman® is a special grade of Guar Gum, specifically developed for the Pharmaceutical industry. Guar Gum is a natural vegetable polymer, and it is obtained by refining and pulverizing the endosperm of the Guar seed - “Cyamopsis Tetragonoloba”. The use of Guar Gum as a Pharmaceutical aid has increased significantly over the last few years. The material has been successfully used as a tablet binding and disintegrating agent; in peptic ulcer therapy; jelly formulations; bulk laxatives; appetite depressants; emulsions and suspensions; lotions and creams, and as a viscosifying and stabilizing agent. Some Pharmaceutical formulators have produced pharmaceutically elegant and therapeutically efficient products, using Guar Gum as an aid, while others have not taken advantage of this versatile gum’s unique properties.

TEMCOL 20 is a Semi-Refined refined and high viscosity and beneficial in most applications.

Pfanstiehl Trehalose T-104-4 is a non-reducing disaccharide consisting of two glucose molecules linked by an α, α–1,1 bond. Pfanstiehl Brand, High Purity Low Endotoxin Trehalose is used in the biopharmaceutical industry to stabilize proteins, lipids, and carbohydrates throughout the formulation and freeze/thaw life cycle of therapeutics. It is also widely applied as a key component in cryopreservation/freeze media to stabilize cell membranes and improve the recovery and robustness of cells used for bioproduction and cell therapy.

TEMCOL 10 is for Ice-Cream, Salad Dressing, Dairy product thickening etc

Pfanstiehl Sucrose S-124-1-MC is a non-reducing crystalline disaccharide made up of glucose and fructose, found in many plants but extracted as ordinary sugar mainly from sugar cane and sugar beets. Pfanstiehl Brand, High Purity Low Endotoxin Sucrose is used in the biopharmaceutical industry to stabilize proteins, lipids, and carbohydrates throughout the formulation and freeze/thaw life cycle of therapeutics. It is also widely applied as a cryopreservative and media supplement in a variety of cell-based bioprocesses. It is preferred to trehalose in applications where solubility and/or viscosity issues are paramount.

CELNY SSL is a water soluble, non-ionic derivative of cellulose, an abundant and natural polysaccharide found in all plants. CELNY™ brand is a high quality grade of HPC for food and nutraceutical use. CELNY is available in a wide range of viscosities and particle sizes to suit your application needs. It is food use approved globally, non-GMO, non-dairy, gluten and common allergen free. CELNY HPC applications include tablet binder, film forming agent, and stabilizer.

CELNY L is a water soluble, non-ionic derivative of cellulose, an abundant and natural polysaccharide found in all plants. CELNY™ brand is a high quality grade of HPC for food and nutraceutical use. CELNY is available in a wide range of viscosities and particle sizes to suit your application needs. It is food use approved globally, non-GMO, non-dairy, gluten and common allergen free. CELNY HPC applications include tablet binder, film forming agent, and stabilizer.

TEMCOL 40 (Clarified, high viscosity, high performing)

Pfanstiehl Maltose M-132-1 is a disaccharide consisting of two glucose molecules with an α-1,4 glucosidic bond. Upon injection, it is only requires a minimal amount of insulin, having little impact influence on blood-sugar levels. Hence, it is commonly used to stabilize intravenous IG infusions, among other protein-based formulations. Pfanstiehl Brand, High Purity Low Endotoxin Maltose is a high quality, pharmaceutical grade maltose that can be used in bioprocessing and parenteral applications. In addition to use in nutritional intravenous fluids in certain countries, it can be also used as an excipient for protein stabilization.

Sarcol FG is Economic industrial use.

CELNY M is a water soluble, non-ionic derivative of cellulose, an abundant and natural polysaccharide found in all plants. CELNY™ brand is a high quality grade of HPC for food and nutraceutical use. CELNY is available in a wide range of viscosities and particle sizes to suit your application needs. It is food use approved globally, non-GMO, non-dairy, gluten and common allergen free. CELNY HPC applications include tablet binder, film forming agent, and stabilizer.

Sidley Chemical H-HPC can be used as a binder in pharmaceutical field such as tablet and particle binder, which can increase the stability and hardness of tablets. H-HPC has excellent film-forming property and film can be tenacious and elastic. It`s also an excellent film coating material.

Hydroxypropyl Cellulose (HPC) is a water soluble, non-ionic derivative of cellulose, an abundant and natural polysaccharide found in all plants. CELNY™ brand is a high quality grade of HPC for food and nutraceutical use. CELNY is available in a wide range of viscosities and particle sizes to suit your application needs. It is food use approved globally, non-GMO, non-dairy, gluten and common allergen free. CELNY HPC applications include tablet binder, film forming agent, and stabilizer.

Lambda carrageenan that although does not gel but can be used to thicken dairy products. In aqueous systems it can act as a suspending and emulsifying stabilizer, thickener, binder and gelling agent.

Kappa Carrageenan that forms strong, rigid gels in the presence of potassium ions, and reacts with dairy proteins. It is sourced mainly from Kappaphycus alvarezii or Euchema Cottoni sea weeds.

Sarda Gums and Chemicals GLUKOM T30 is high viscosity Konjac Gum. Mainly Used in Bakery products, Beverages, Carbonated beverages, Concentrates and ades, Confectionary, Desserts, Dough conditioners, Edible films, fiber drinks, Formed foods, Frozen foods, Glazes, Gravies, Ice cream, Jellies, Meat, Meat products, Non-dairy creamers, Noodles, Pasta, Pudding, Cream, Yogurt.

Pfanstiehl Arginine A-170 is a L-Arginine, High Purity / Low Endotoxin-Low Metals, USP/EP/JP/ChP.

CELNY VH is a water soluble, non-ionic derivative of cellulose, an abundant and natural polysaccharide found in all plants. CELNY™ brand is a high quality grade of HPC for food and nutraceutical use. CELNY is available in a wide range of viscosities and particle sizes to suit your application needs. It is food use approved globally, non-GMO, non-dairy, gluten and common allergen free. CELNY HPC applications include tablet binder, film forming agent, and stabilizer.

Sarda Gums and Chemicals Aquacol grade CMC is range of Sodium carboxymethyl cellulose (NaCMC) are made with highly optimized conditions to convert cellulose in soluble polymers. Often they are considered as most effective water binders for use in food and non-food applications. Benefits of using Aquacol grades go far beyond being a cost-effective solution. High water-solubility and high water biding capacity help impart a number of property enhancements that bring high stability of texture etc. Not just that, they also provide food grade adhesion to enable creative food applications beside non-food types.