Knowde Enhanced TDS
Identification & Functionality
- Carrier
- INCI Name
- Ingredient Origin
- Cosmetic Ingredients Functions
- Technologies
- Product Families
- Origin
- Holy Basil OSP is a proprietary extract of Ocimum sanctum that is water-miscible and optimized for high concentrations of components with strong anti-inflammatory and skin-soothing activities
Features & Benefits
- Benefit Claims
- Labeling Claims
- Benefits & Claims
- Plant-derived active produced from Holy Basil (tulsi)
- Rich in polyphenols and contains pentacyclic triterpenoids including ursolic acid, betulinic acid, and oleanolic acid
- Provides antioxidant activity against environmental stress
- Protects the extracellular matrix (ECM) via inhibition of proteolytic stress
- Enhances expression of 15 genes important for ECM structure and fundamental cellular interactions
- Inhibits COX-2 activity for modulation of inflammation
- Inhibits production of inflammatory mediators: IL-1α, IL-6, IL-8, and MCP-1
- Inhibits the inflammatory effects of urban air pollution
Applications & Uses
- Markets
- Color Cosmetic Applications
- Skin Care Applications
- Sun Care Applications
- Use Level
- 0.5 - 2.5%
- Applications
- De-stressing & anti-aging regimes targeting oxidative and proteolytic damage (pollution, UV exposure, etc.)
- Soothing and calming products for sensitive skin
- Skincare products targeted towards millennials and young consumers (for skin protection & aging prevention)
- Formulas to treat mild-to-moderate blemishes in young and adult consumers
- Emulsions, creams, and lotions
- Pre- and post-sun skin care
- BB creams, CC creams, and color formulations
- Compatibility and Formulation
- Holy Basil OSP is compatible with most conventional ingredients used in skincare products. It is miscible in aqueous and glycolic systems and tolerates a pH range of 3-7. Best if added in last step of the formulation process when temperature is below 50°C. If needed, it can be added to the formula during its cooling phase at temperatures up to 75°C. Mix well before use.
Properties
- Physical Form
Regulatory & Compliance
- Certifications & Compliance
- Regulatory Information
- This product has not been tested on animals, and our company adheres to the written provisions of such animal rights organizations as Leaping Bunny and Cruelty/Free International.
- This product contains no animal products. It is manufactured using only plant based or synthetically derived (non-animal origin) materials and is thereby declared a Vegan Product.
- All materials used to produce this product are procured using sustainable sourcing practices.
- This product is manufactured in accordance with the current Good Manufacturing Practices (cGMP) requirements established by the U.S. Food and Drug Administration (FDA) for cosmetics. Furthermore, Biocogent, LLC, and this production facility(ies), are registered as cosmetic manufactures with the FDA.
- REACH compliance: All of the ingredients (substances) used in the manufacture of this product (mixture)are either registered under REACH, or qualify for an Article 2 (low volume of less than 1 metric ton), Annex IV or Annex V exemption, making our product REACH compliant.
- Proposition 65 compliance: Based upon Biocogent LLC’s knowledge of our business operations and chemical formulations, no chemicals listed by the State of California Environmental Protection Agency are used in our products, or as a processing aid for any product manufactured in our facility.
Technical Details & Test Data
- Test Data
Holy Basil OSP Inhibition of DPM 2.5-Induced IL-6
Holy Basil OSP significantly reduces the levels of IL-6, a pro-inflammatory cytokine that is elevated in keratinocytes upon air pollution exposure (DPM2.5).
Safety & Health
- Safety
- Human Repeat Insult Patch Testing (HRIPT) under semi-occlusive conditions indicated that Holy Basil OSP is not a primary skin irritant or a primary skin sensitizer when tested neat. EpiOcular testing predicted that Holy Basil OSP would be a Minimal ocular irritant at recommended use levels.
Storage & Handling
- Shelf Life
- 18 Months
- Storage Condition
- Holy Basil OSP should be stored at room temperature in original packaging away from heat and light.