Products

Grandiciin® (R10124) is an Epimedium extract featuring a beneficial mix of prenylated flavonoids for addressing blemished skin. Applications for Grandiciin® include microbiome-balancing products, anti-blemish and spot treatments, anti-sebum and oil-reducing hair and skin care, and soothing and calming body care regimens for damaged skin. Grandiciin® improves skin health and wellness through microbiome-rebalancing activity, reducing the problematic Cutibacterium acnes (formerly Propionibacterium acnes) biofilms that contribute to inflammation, redness, and blemish formation. Grandiciin® is clinically shown to diminish C. acnes burden on the skin while also reducing sebum (oil) production and signs of inflammation and redness and improving the appearance of blemishes in four weeks. Grandiciin® addresses inflammatory, proteolytic, and oxidative stress to provide an extra layer of protection against tissue damage and scarring in severely blemished skin.

Advanced Solutions MariMoist® KPF (R10097) is a sustainable marine biopolymer derived from Chondrus crispus aquatic plants with bio-derived high molecular weight hyaluronic acid (HA), a glycosaminoglycan that is an important natural component of skin. Referred to as the “aloe of the ocean,” MariMoist® KPF is a water-soluble, viscous, hydrocolloid-flowing gel with the highest standards of consistency, quality, and purity.   MariMoist® KPF provides water delivery and a unique textural sensation, improving the aesthetic and tactile properties of finished products while helping to build “body” and impart a rich, luxurious feel. MariMoist® KPF has been demonstrated to bind and deliver water for optimal hydration of the skin, scalp, and hair. Acting as a humectant, MariMoist® KPF is an emollient liquid that instantly moisturizes and softens dry skin.   Applications for MariMoist® KPF include an emollient and hydrator in skin and hair products and a formulation aid or aesthetic modifier of product viscosity and body. MariMoist® KPF is an excellent base for formulations.

DermalRx® CKW (R10091) is a plant-derived combinatorial curcuminoid extract that potently and dose-dependently modulates excess sebum production by inhibiting type I and type II 5α-reductase. Clinical evaluation showed significant reductions in sebum production and a visible decrease in facial sheen. DermalRx® CKW is ideal for sebum-regulating products for skin and hair applications, as well as anti-blemish and pore-minimizing formulations.

Pleiotanicals® Volpura® EP (R10098) is an Echinacea purpurea extract to address the signs of aging by supporting the skin’s natural plumping processes. Volpura® EP activates adipogenesis (fat production) within the skin to combat the appearance of wrinkles and sagging from deep within the tissue. Volpura® EP restores fuller, youthful-looking skin by activating an adipogenic modulator that increases the number and size of fat-producing cells. Clinical studies demonstrate that Volpura® EP improves skin mechanical properties with volumizing, anti-wrinkle activity reported after use on the face and hands for 12 weeks. Volpura® EP is recommended for anti-wrinkle, anti-aging, firming, plumping, topical contouring, and volumizing products, as well as regimens to address age-related lipoatrophic disorders.

Cogesome® RL (R10115) is a novel and proprietary pro-liposome formulation that encapsulates retinol (vitamin A) for superior penetration into the skin, improved stability, and optimal miscibility in aqueous systems. The power of retinol is undisputed, accelerating epidermal renewal and enhancing collagen and hyaluronic acid production to reduce the appearance of fine lines, wrinkles, and other signs of aging and improve the skin’s overall appearance. Properly managed retinol is one of the skin’s best supporters, contributing to a healthy glow and youthful appearance.Ex vivo data demonstrate how Cogesome® RL rapidly penetrates the skin, enhancing the penetration and delivery of retinol from the skin’s surface deep into the skin to maximize efficacy. Cogesome® RL significantly reduces biofilm-forming skin resident Cutibacterium acnes, a microbial culprit of blemish flare-ups and skin inflammation. Cogesome® RL is well suited for applications in anti-aging, anti-wrinkle, and anti-blemish formulas, skin exfoliating and resurfacing products, and regimens targeting sun damage and hyperpigmentation.

HEDI® Shea Butter SF (R10105) is a unique water-based microdispersion of shea butter with organic-certified babassu oil, plant-derived squalane, sunflower-derived phospholipids, and vitamin E. The triglycerides (fat) in shea butter are derived mainly from stearic acid and oleic acid. Organic certified babassu oil is extracted from wild-picked fruits of the babassu palm tree, offering softening properties with glycerides of lauric, myristic, and oleic acids. HEDI® Shea Butter SF is an excellent emollient, conditioner, and moisturizer that revitalizes dull, dry skin and promotes skin renewal. Applications for HEDI® Shea Butter SF include moisturizing treatments for very dry, rough, and cracked skin, skincare products for sensitive skin, and skin, scalp, and hair care conditioning formulas. HEDI® Shea Butter SF can be used in many care products, such as moisturizing creams and emulsions, sunscreens, lip gloss, makeup primers, facial masks, sunless tanning products, hair conditioners, and soaps.HEDI® products are stable ingredient blends of aqueous and oil-based materials made using a unique manufacturing process. HEDI® products are ultra-concentrated homogeneous constructs that are infinitely dilutable in aqueous systems. HEDI® products have superior aesthetics while simplifying formulation and manufacturing processes and enhancing the delivery of active ingredients in the formula. HEDI® products can be adjusted to achieve a consistency that is milk-like (pourable and even sprayable), creamy, or paste-like. Tactile properties can be light and silky or velvety and more occlusive. HEDI® products streamline manufacturing processes for time, energy, and cost savings by avoiding additional heating, melting, and mixing steps. HEDI® products are amenable to cold processes and do not require surfactants or emulsifiers.HEDI® products have properties similar to the skin barrier, promoting skin permeability and facilitating delivery through the lipid-rich, waterproof stratum corneum. Finished products have a better feel and provide superior surface coverage when compared to traditionally formulated butters and oils.

DermalRx® SRC-R (R10099) is a yeast-derived oligopeptide that promotes skin renewal by stimulating natural exfoliation via gentle and selective desquamation. Clinical testing demonstrates that DermalRx® SRC-R enhances exfoliation to reduce skin roughness and improve the appearance of wrinkles in four weeks. DermalRx® SRC-R gently loosens coarse keratinized cells at the surface, delivering results for applications in anti-aging, anti-wrinkle, anti-blemish, skin brightening, and exfoliation products. DermalRx® SRC-R is clinically demonstrated to restore skin texture and radiance with documented improvements in the appearance of hyperpigmentation, wrinkles, and other signs of aging. DermalRx® SRC-R is a selective exfoliant for safe, effective skin renewal.

Pleiotanicals® Holy Basil OSE (R10104) is a proprietary extract of Ocimum sanctum (a plant used in Ayurvedic medicine) for pollution protection and aging prevention in the skin. Holy Basil OSE contains key active molecules, including polyphenols and pentacyclic triterpenoids, that protect against environmental pollution with anti-aging benefits. Holy Basil OSE is ideal for anti-aging, anti-wrinkle, de-stressing, and pollution/UV protection regimens, as well as soothing, calming products for sensitive skin.   Holy Basil OSE reduces a suite of inflammatory mediators in the skin typically induced by exposure to airborne particular matter (PM2.5). Holy Basil OSE protects the extracellular matrix (ECM, the structural foundation of the skin) against damaging oxidative, proteolytic, and inflammatory stress while also modulating collagen and other genes fundamental for ECM structure and integrity.

Pleiotanicals® Holy Basil OSP (R10110) is a proprietary extract of Ocimum sanctum (a plant used in Ayurvedic medicine) for pollution protection and aging prevention in the skin. Holy Basil OSP contains key active molecules, including polyphenols and pentacyclic triterpenoids, that protect against environmental pollution with anti-aging benefits. Holy Basil OSP is ideal for anti-aging, anti-wrinkle, de-stressing, and pollution/UV protection regimens, as well as soothing, calming products for sensitive skin.   Holy Basil OSP reduces a suite of inflammatory mediators in the skin typically induced by exposure to airborne particular matter (PM2.5). Holy Basil OSP protects the extracellular matrix (ECM, the structural foundation of the skin) against damaging oxidative, proteolytic, and inflammatory stress while also modulating collagen and other genes fundamental for ECM structure and integrity.

Pleiotanicals® Scavenox® HH (R10109) is a highly stable green tea extract with epigallocatechin gallate (EGCG) for long-term antioxidant, anti-inflammatory, and skin-brightening activity. Applications for Scavenox® HH include anti-aging and anti-blemish regimens, skin-brightening and skin tone-balancing systems, and soothing and calming products for sensitive skin. Scavenox® HH protects the skin from oxidative stress with the demonstrated ability to prevent UV-induced lipid peroxidation and scavenging of singlet oxygen. Scavenox® HH also inhibits inflammatory and proteolytic (MMPs and elastase) damage for protection against UV radiation, pollution, and other environmental stressors. These activities offer skin protection and renewal by preserving collagen and other components of the extracellular matrix (ECM, the structural foundation of the skin). Scavenox® HH prevents excessive melanin production to combat hyperpigmentation by inhibiting tyrosinase activity.

Pleiotanicals® Volpura® EPO (R10125) is a plant-derived active ingredient extracted from Echinacea purpurea, known for its abundance in various active compounds, notably fatty acid alkylamides. This ingredient demonstrates the ability to activate PPAR-γ, which serves as the master regulator of adipogenesis. Its benefits lie in enhancing fat production by stimulating the differentiation of pre-adipocytes into adipocytes. This property makes it suitable for incorporation into formulations targeting anti-wrinkle effects, particularly for addressing expression lines in the forehead and nasolabial fold areas. Additionally, it finds application in facial contouring, re-firming, and plumping regimens aimed at addressing age-related lipoatrophy.