Products in Pharmaceuticals & Nutraceuticals: Orally Disintegrating ...

PEARLITOL® Flash is used in nutraceutical and pharma oral dosage forms as a filler/binder for orally dispersable tablets. Applications Fast disintegrating tablets Orally dispersible tablets Benefits Excipient functional properties Disintegrant benefit Simplifies tablet formulation Features Compound of mannitol and starch adapted to direct compression formulation Excellent chemical inertness Consistent rapid disintegration under any compression force

NUTRIOSE® FM06 Dextrin can be used to add dietary fiber to capsules, films, granules, lozenges and other pharmaceutical applications. Benefits BSE-free Gluten-free Halal and Kosher certified Melamine-free Non-GMO Non-Hazardous TSE-free Vegan Features Chemical stability Easy dispersability

SOLUTAB® Croscarmellose sodium is used in pharmaceutical and nutraceutical applications as a superdisintegrant for various oral dosage forms. Applications Swallowable tablets Orally dispersible tablets Hard capsules Blends Granules Pellets premix Benefit Efficient disintegration at low use level Features Crosslinked carboxymethyl cellulose sodium Three grades are available Disintegration performance is obtained through the wicking and swelling capacity that can be maximized via the selection of its origin (wood or cotton) Can be adapted to wet and dry granulation or direct compression processes

GLYCOLYS® Low Solvent Sodium Starch Glycolate is a superdisintegrant for pharmaceutical and nutraceutical swallowable tablets, orally dispersible tablets and hard capsules. Features Different grades designed to meet specific needs: Withstanding high shear granulation Acidic conditions Low organic solvent content

MICROCEL® Microcrystalline cellulose is used in pharmaceutical and nutraceutical applications as a filler/binder and fiber source in various oral dosage forms. Applications Swallowable tablets Hard capsules Blends Granules Pellets premix Features Available in a large range to meet different formulation, process and dosage form requirements Large surface area allows adsorption of particles or liquids and a certain capacity to act as a disintegrant Spray dried and offered from EXCiPACT (International Pharmaceutical Excipients Certification) certified plant

POLYSORB® 85/70/00 Partially dehydrated sorbitol liquid is a plasticizer in soft capsules and orally dissolving films. It can be used in pharmaceutical dosage forms.POLYSORB® 85/70/00 is an aqueous solution of D-sorbitol and 1.4- sorbitans that has been developed by Roquette as a plasticizer for soft gelatine capsule applications. The advantage of this product in soft gels relates to its remarkable compatibility with gelatin that ensures no migration over time thereby preventing any defects like graining when crystallizing plasticizers are used or leaching phenomena either into the filler media or at the surface of the soft gel.

KLEPTOSE® HPB Oral Grade is a solubilizer and stabilizer for pharmaceutical and nutraceutical oral dosage applications. Applications Swallowable, chewable and effervescent tablets Lozenges Hard and soft capsules Orally dissolving films Blends Granules Pellets premix Medicated confectionary Syrups Suspensions Liquids Cream Paste Semi-solids Benefits Improves the solubility of poorly soluble compounds Can be used for taste masking of bitter or unpleasant active ingredients

StarLac® Co-processed lactose starch is a filler/binder with strong disintegrant properties. The co-processing offers superior benefit compared to a blend of lactose and starch. It allows to improve the performance (hardness, friability, disintegration time) of your formulation. Specifically designed for direct compression applications, StarLac® is also an excellent filler/binder in dry granulation processes. StarLac® can be used in various oral dosage forms in pharmaceutical applications including granules, swallowable tablets, orally dispersible tablets and hard capsules.

MICROCEL® Microcrystalline cellulose is used in both pharmaceutical and nutraceutical applications as a filler/binder and fiber source in various oral dosage forms. Applications Swallowable tablets Hard capsules Blends Granules Pellets premix Features Available in a large range to meet different formulation, process and dosage form requirements Large surface area allows adsorption of particles or liquids and a certain capacity to act as a disintegrant Spin flash-dried

GLYCOLYS® Sodium Starch Glycolate is a superdisintegrant for pharmaceutical applicationbs such as swallowable tablets, orally dispersible tablets and hard capsules. Benefits BSE-free Halal and Kosher certified Melamine-free Non-GMO Non-hazardous TSE-free Vegan Features Free of off-odors Low ethanol content

PEARLITOL® Mannitol pharma range is used in pharmaceutical and nutraceutical formulations as a filler, filler/binder and bulk sweetener in various oral dosage applications. Applications Swallowable, orally dispersible, chewable and effervescent tablets Lozenges Blends Granules Pellets premix Medicated confectionery Features Unique blend of exceptional physical and chemical stability and no hygroscopicity Directly compressible crystalline range with various particle sizes Great organoleptic, non-cariogenic and sugar-free properties Suitable for use in formulations addressing pediatric and diabetic patient populations

Roquette powdered NF corn starch is used in pharmaceutical and nutraceutical formulations as a disintegrant, filler and binder (once cooked). Applications Swallowable tablets Hard capsules Blends Granules Pellets premix

PEARLITOL® 25 C Mannitol is a filler and bulk sweetener that can be used for pharmaceutical oral dosage applications. Benefits BSE-free Halal and Kosher certified Melamine-free Non-carcinogenic Non-hazardous Sugar-free TSE-free Vegan Features High physical and chemical stability Cooling effect Non-cariogenic Low hygroscopicity

NEOSORB® Sorbitol pharma is used in pharmaceutical and nutraceutical formulations as a filler, filler/binder and bulk sweetener in various oral dosage applications, and as a plasticizing agent well-adapted to starches in coating/film forming applications. Applications Swallowable, orally dispersible, chewable and effervescent tablets Lozenges Blends Granules Pellets premix Medicated confectionery Features Excellent tableting properties Great organoleptic, non-cariogenic and sugar-free properties Suitable for use in formulations addressing pediatric and diabetic patient populations

PEARLITOL® 200 GT-EXP is a direct compression excipient specifically formulated to enhance the manufacturing process of tablets. This exceptional excipient is designed to address key challenges such as capping, while improving flowability and tabletability. PEARLITOL® 200 GT-EXP is a granulated form of mannitol known for its outstanding physical and chemical stability. With its high API compatibility and non-hygroscopic nature, it ensures consistent quality and performance in pharmaceutical formulations. As a non-cariogenic and non-acidogenic sugar-free sweetener, it is suitable for various patient populations, including pediatric and diabetic individuals. PEARLITOL® 200 GT-EXP finds application in a wide range of dosage forms, including tablets (lozenges, swallowable, orally dispersible, chewable, and effervescent) as well as powder blends (sachets, oral stick packs, and hard gelatin capsules).

PEARLITOL® Mannitol pharma range is used in pharmaceutical and nutraceutical formulations as a filler, filler/binder and bulk sweetener in oral dosage form applications. Applications Swallowable, orally dispersible, chewable and effervescent tablets Lozenges Blends Granules Pellets premix Medicated confectionery Features Unique blend of exceptional physical and chemical stability and no hygroscopicity Directly compressible crystalline range with various particle sizes Great organoleptic, non-cariogenic and sugar-free properties Suitable for use in formulations addressing pediatric and diabetic patient populations

Roquette 400L-NF Corn Starch is an oxidized maize starch that can be used as a disintegrant filler and binder (once cooked) in a variety of nutraceutical and pharmaceutical dosage forms, including swallowable tablets, hard capsules, blends, granules and pellets premix. Benefits Acrylamide-free BSE-free Halal and Kosher certified Melamine-free TSE-free Vegan

PEARLITOL® Mannitol is used in pharmaceutical and nutraceutical formulations as a filler, filler/binder and bulk sweetener in various oral dosage applications. Applications Swallowable, orally dispersible, chewable and effervescent tablets Lozenges Blends Granules Pellets premix Medicated confectionery Features Unique blend of exceptional physical and chemical stability and no hygroscopicity Directly compressible crystalline range with various particle sizes Great organoleptic, non-cariogenic and sugar-free properties Suitable for use in formulations addressing pediatric and diabetic patient populations

PEARLITOL® 160 C - Mannitol is a versatile excipient for nutraceutical and pharmaceutical oral dosage applications.  Suitable for use in capsules, granules, orally disintegrating tablets (ODTs), powders, and tablets, PEARLITOL® 160 C supports direct compression manufacturing. It boasts high physical and chemical stability, and it is non-hygroscopic, ensuring long-lasting quality. Ideal for healthcare and pharma , this excipient enhances drug delivery and care solutions with its excellent performance and stability.

PEARLITOL® Mannitol pharma range is used in pharmaceutical and nutraceutical applications as a filler, filler/binder and bulk sweetener for various oral dosage forms. Applications Swallowable, orally dispersible, chewable and effervescent tablets, Lozenges Blends Granules Pellets premix Medicated confectionery Benefit Suitable for use in formulations addressing all types of patient populations, including pediatric and diabetic Features Directly compressible Unique blend of exceptional physical and chemical stability No hygroscopicity Organoleptic, non-cariogenic and sugar-free properties

Atomgrid Paracetamol USP (Acetaminophen USP ) is a water-soluble powder used as an API intermediate in pharmaceutical and nutraceutical applications. It meets the standards set by the United States Pharmacopeia (USP) and is specifically formulated for orally disintegrating tablets (ODTs), ensuring effective dosage and rapid dissolution

L-HPC (low-substituted hydroxypropyl cellulose NF, JP, EP) This dual functioning excipient acts as both a disintegrant and binder. It is not the same as HPC. L-HPC is insoluble in water. It is an effective disintegrant due to its swelling action in water. Because is has good compressibility, it functions as a dry binder.NBD Grades:Better flowability because of the non-fibrous particle shapeBetter compressibilityBetter tasteEnhanced stability because it is non-ionic and has low water activityIt is peroxide free and provides excellent compatibility for oxygen sensitive APIsA variety of grades are available depending on the application. L-HPC NBD-022 is suitable for direct compression and ODTs.

SmartEx® is a co-processed excipient which consists of L-HPC, D-mannitol and fully hydrolyzed polyvinyl alcohol (PVA) and it specially designed for orally disintegration tablets (ODTs) and also immediate release tablet formulation by direct compression. All the excipients are widely used in pharmaceutical industry. One of the main advantage over other co-processed excipients is that SmartEx® contains L-HPC and therefore gives excellent stability.

SmartEx® is a co-processed excipient which consists of L-HPC, D-mannitol and fully hydrolyzed polyvinyl alcohol (PVA) and it specially designed for orally disintegration tablets (ODTs) and also immediate release tablet formulation by direct compression. All the excipients are widely used in pharmaceutical industry. One of the main advantage over other co-processed excipients is that SmartEx® contains L-HPC and therefore gives excellent stability.

CompactCel® DIS is a natural/organic super-disintegrant which enables a rapid break-up of solid dosage forms when they come into contact with moisture. The super-disintegrant premix is formulated with natrual ingredients which complies with current Clean Label Standards. It provides an alternative to synthetic super-disintegrants, such as crosslinked polymers, crosscarmellose sodium or sodium starch glycolate. CompactCel® DIS helps in the fast breakdown of the solid dosage form so that the active ingredient becomes bioavailable faster and is readily absorbed. It can be also used in the formulation of oral disintegrating tablets (ODT) or chewing tablets.

Ibuprofen DC 100 are spherically shaped particles consisting of 100 % Ibuprofen drug substance.Due to its shape and surface structure Ibuprofen DC 100 provides unique product characteristics offering a wide range of applications.

Off white free flowing granules.

Off white free flowing granules.

DICOM SANAQ® LS 004 have average particle size of 300 - 550 microns. It is a combination of Lactose Monohydrate and Starch (maize). Lactose is water loving and soluble in water, at high compression force it hampers disintegration. Starch has multifunction characters and act as binder as well as disintegrant. Starlose has optimized composition of these two ingredients.

Off white free flowing granules.

Off white free flowing granules.

Off white free flowing granules.

SSG SANAQ® Type A is Blue color with iodine reagent

Fujicalin® is a dibasic calcium phosphate anhydrous designed to function as a direct compression excipient. It has exceptional flow and compression characteristics, while maintaining the ability for rapid disintegration. The key to Fujicalin®’s superior performance is the highly specialized and proprietary manufacturing process that yields a unique primary particle.

F-Melt® Type F1 is a proprietary co-spray dried excipient launched by Fuji in 2005. F-Melt® is designed not only for manufacturing orally disintegrating tablets (ODTs) and tablets that dissolve fast in the oral cavity without the need of water, but is also an excellent excipient for soft chewable tablets. It is suitable for manufacturing directly compressible ODTs simply by blending with active pharmaceutical ingredients (APIs) and lubricants. F-Melt® Type F1 is mainly used for dietary supplement applications.

F-Melt® Type C is a proprietary co-spray dried excipient launched by Fuji in 2005. F-MELT® is designed not only for manufacturing orally disintegrating tablets (ODTs) and tablets that dissolve fast in the oral cavity without the need of water, but is also an excellent excipient for soft chewable tablets. It is suitable for manufacturing directly compressible ODTs simply by blending with active pharmaceutical ingredients (APIs) and lubricants. F-MELT® Type C is mainly used for pharmaceutical and nutraceutical applications.