PEARLITOL® 160 C - Mannitol

1 of 13 products in this brand
PEARLITOL® Mannitol pharma range is used as a filler and filler/binder. The PEARLITOL® range offers a unique blend of exceptional physical and chemical stability with no hygroscopicity. Using different texturizing technologies, we have designed a crystalline range of directly compressible PEARLITOL® with various particle sizes, allowing you to find the right product. With great organoleptic, non-cariogenic, and sugar-free properties. PEARLITOL® is suitable to be used in formulations addressing all types of patient populations, including paediatrics and diabetics.  PEARLITOL® can be used in various oral dosage forms in both pharmaceutical and nutraceutical applications, including swallowable tablets, orally dispersible tablets, chewable tablets, effervescent tablets, lozenges, blends, granules, pellet premixes, and medicated confectionary.

Chemical Name: D-mannitol

Functions: Binder, Filler, Sweetener

CAS Number: 69-65-8

Dosage Form: Capsules, Granules, Orally Disintegrating Tablets (ODTs), Powder & Powder Blends, Tablets

Labeling Claims: Non-Cariogenic, Sugar-free

Synonyms: 1,2,3,4,5,6-Hexanehexol, Cordycepic Acid, D-(-)-Mannitol, Manicol, Manitol

Safety Data Sheet

Knowde Enhanced TDS

Identification & Functionality

Chemical Name
Pharma & Nutraceuticals Functions
Chemical Structure

Features & Benefits

Applications & Uses

Manufacturing Technology
Applications

PEARLITOL® 160 C is dedicated to nutraceutical and pharmaceutical oral dosage applications needing the benefit of a filler as well as a bulk sweetener. It is a sugar-free and non-cariogenic excipient with very high physical and chemical stability and no hygroscopicity

Properties

Solubility
Appearance
White or almost white crystalline powder
Taste
Pleasant taste slight sweetness and cooling effect
Odor
Odorless
Soluble in
Water
Insoluble in
Ethanol
Typical Properties
ValueUnitsTest Method / Conditions
Molecular Weight182.2g/mol
Water Content (LOD)max. 0.5%
Melting Temperature169°C
Average Mean Particle Diameter160µm
Particle Size Distribution
ValueUnitsTest Method / Conditions
dv1032µm
dv50160µm
dv90315µm
Powder Characteristics
ValueUnitsTest Method / Conditions
Bulk Density0.64g/cm³
Tapped Density0.69g/cm³
True Density1.514g/cm³
Specific Surface Area0.25m²/g
Solubility
ValueUnitsTest Method / Conditions
Soluble in Water (at 25°C)216mg/ml

Regulatory & Compliance

Technical Details & Test Data

Morphology

Water Sorption Isotherm (at 20°C)

Packaging & Availability

Packaging Information

 

25 KG