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Calcidone® is the calcium salt of L-pyrrolidone carboxylic acid (L-PCA). It is obtained by the cyclization of L-glutamic acid, an amino acid of plant origin. This product is a combination of calcium and L-PCA, which helps the skin to carry out or regain its role as a barrier by stimulating the cell differentiation process and activating the synthesis of total epidermal lipids, notably ceramides. Calcidone® also has strong anti-MMP1 activity, which helps to preserve the skin's integrity.

INCI Name: Calcium PCA

Functions: Skin Barrier Protectant

Labeling Claims: Credo Clean Standard, Preservative-free, Ulta Beauty's Conscious Beauty

Certifications & Compliance: COSMOS, ECOCERT GREENLIFE, IECIC (China), ISO 16128

Benefit Claims: Anti-Aging, Skin Barrier, Skin Strengthening Effect, Specific Sensory Performance, Stimulating, Suitable for Sensitive Skin

Knowde Enhanced TDS

Identification & Functionality

INCI Name
Cosmetic Ingredients Functions
CAS No.
31377-05-6
EC No.
250-602-4

Features & Benefits

Applications & Uses

Skin Care Applications
Use Level
0.5 - 3%
Applications
  • Care for dry to very dry skin
  • Care for sensitive skin
  • Care for stressed and tired skin
  • Anti-aging care for mature skin

Properties

Physical Form
Preservatives

None

Regulatory & Compliance

Regulatory Status
  • Authorized for use in EU, USA, Japan, China and under conditions in Australia and Canada.
  • Raw material approved by ECOCERT GREENLIFE , compliant with the COSMOS Standard.

Technical Details & Test Data

Mechanism of Action

Considered as a second messenger participating inall of the body's biochemical reactions, calcium is the trace element that triggers the differentiation phases of the cells of the epidermis. Calcidone® , combination of calcium and L-PCA, allows the skin to ensure or regain its barrier roleby stimulating the process of cell differentiationandactivating the synthesis of total epidermal lipids, and in particular ceramides. Calcidone® also exhibits strong anti-MMP1 activity and therefore preserves skin integrity.

Packaging & Availability

Regional Availability
  • Australia
  • Canada
  • China
  • Europe
  • Japan
  • USA