Products in Pharmaceuticals & Nutraceuticals: Binder

T-Det® PEG 4000 F is a water-soluble polymer made from ethylene oxide. It has a wide range of applications as a humectant and viscosity modifier in the cosmetic and personal care industries, a mold release agent and lubricant in the rubber industry, and a binder and dry lubricant for pill and tablet manufacture in the pharmaceutical industry.

MASCEROL™ Glycerine 99.7 USP, non-GMO is highly refined with a minimum glycerol content of 99,7%. MASCEROL™ Refined Glycerine is used as a base ingredient in personal care preparations. It provides moisturizing properties and improves skin permeability. It is a gentle ingredient for anti-aging and anti-irritant cosmetics, found in skin & hair care applications, shaving cream, soaps & water-based lubricants. MASCEROL™ Refined Glycerine is used as an excipient in pharmaceutical production and preparations for improving smoothness, providing lubrication, and because of its humectant characteristics. It is found in allergen immunotherapies, cough syrups, tinctures, elixirs & expectorants. It is a tablet-holding agent and a key ingredient in soft gelatin capsules. In food as well as beverage applications MASCEROL™ serves as a humectant or wetting agent, solvent, sweetener or sugar substitute (approx. 60 % as sweet as sucrose), thickening agent, or filler.

MASCEROL™ Glycerine 99.7 USP, non-GMO, RSPO MB is highly refined with a minimum glycerol content of 99.7%. MASCEROL™ Refined Glycerine is used as a base ingredient in personal care preparations. It provides moisturizing properties and improves skin permeability. It is a gentle ingredient for anti-aging and anti-irritant cosmetics found in skin and hair care applications, shaving cream, soaps, and water-based lubricants. MASCEROL™ Refined Glycerine is used as an excipient in pharmaceutical production and preparations for improving smoothness, providing lubrication, and because of its humectant characteristics. It is also found in allergen immunotherapies, cough syrups, tinctures, elixirs, and expectorants. It is a tablet-holding agent and a key ingredient in soft gelatin capsules. In food as well as beverage applications, MASCEROL™ serves as a humectant or wetting agent, solvent, sweetener, or sugar substitute (approximately 60% as sweet as sucrose), thickening agent, or filler.

ADM Dextrose Monohydrate is produced through the enzymatic hydrolysis of starch, followed by purification, concentration, crystallization, and drying. It is a white calibrated powder with a refreshing sweet taste and bland odor, complying with EU and manufacturing country directives and regulations on foods and food ingredients, considered Non GMO. Dextrose, also known as glucose, is a simple sugar derived from various botanical sources like corn, wheat, fruits, and honey. It is widely used in a variety of products, including pharmaceutical applications, owing to its versatile functionality and benefits beyond sweetness.

ADM PharmaPlus Native Corn Starch 102 is a food-grade, native maize starch that appears as a fine, matte, white to slightly yellowish powder with a neutral odor and taste. This non-GMO product meets the requirements of the European Pharmacopeia (Ph.Eur.) and is Kosher and Halal certified.

UNIDEX® Agglomerated Dextrose - 020540 is an agglomerated dextrose monohydrate product with maltodextrin. UNIDEX® has a very uniform coarse particle size profile and provides a range of functional benefits in Pharma tableting. It is very compressible to be used as a binder for direct compression, helping the tablet to remain intact during handling and transportation. It can also be used as an effective bulking agent, making it easier to handle the tablet during the manufacturing process. It has excellent flowability, reducing the risk of sticking and clogging during the tableting process.

CERELOSE® Coarse Dextrose NF - 020350 is a coarse monohydrate dextrose product designed for applications requiring a unique coarser particle size profile, rounded and porous particle shape. This free-flowing material is manufactured according to IPEC cGMPs and tested for compliance with Dextrose Excipient NF standards. It can be used as an effective bulking agent in tablets, capsules, and other solid dosage forms to increase their volume and improve their handling properties besides having good compression ability. It meets the requirements of USP/ NF.

UNI-PURE® F - 03451006 is a native corn starch. It is extra-white and free-flowing with not more than 15% moisture. It can be used as a Filler/Disintegrant for both hard-shell capsules and tablet dosage forms. When cooked in an aqueous system, it develops viscosity and sets to a firm gel upon cooling. The multi-compendial UNI-PURE® F meets the requirements of USP/NF, Ph. Eur., and JPE Pharmacopeias.

Pharm-Rx Microcrystalline Cellulose (MCC 102) is a binder for pharma and nutraceuticals. Ingredient list includes microcrystalline cellulose.

Pharm-Rx Inositol Granular is a versatile ingredient with multiple functions, serving as a supplement, filler, and binder. It is well-suited for various applications in the food and pharmaceutical industries. Labeling claims of being naturally derived and plant-based, aligns with the growing demand for products with natural origins. The physical form is available in granules, powders, and solids, providing flexibility in formulation.

Pharm-Rx Povidone, also known as polyvinylpyrrolidone copolymer, serves as a binder within pharmaceuticals and nutraceuticals. Operating in over-the-counter (OTC) capacities, it falls under binders and disintegrants within excipients. Povidone is commonly used in various formulations for its binding properties in pharmaceuticals.

Pharm-Rx Microcrystalline Cellulose (MCC 101) is a binder ingredient for pharma and nutraceuticals. Made of microcrystalline cellulose, it enhances product formulation.

VEEGUM® EZ Magnesium Aluminum Silicate is a unique acidic smectite clay that produces dispersions in the 4.2 - 5.2 pH range for optimum compatibility with the naturally acidic pH of the skin. VEEGUM® EZ one of the easiest of all the grades to hydrate. VEEGUM® EZ is a direct offset for VEEGUM® Ultra and does not contain titanium dioxide.

VANATURAL® MC Bentonite Clay is a rapidly hydrating, water-washed bentonite clay. VANATURAL MC is a pure and natural suspension stabilizer, emulsion optimizer and rheology modifier for all topical products. VANATURAL MC is tightly controlled for microbiology. VANATURAL MC disperses easily into water and hydrates rapidly. VANATURAL MC also reduces the slippery or sticky feel of gums and polymers, while providing a silky, tack-free feel in topical preparations. This bentonite clay is synergistic with common thickeners such as VANZAN® xanthan gum and CMC. These combinations will provide greater thickening, stabilizing and suspending properties than those developed by the individual components of the mixture.

VEEGUM® HV Magnesium Aluminum Silicate provides excellent emulsion and suspension stability at low use levels. This grade is used in a variety of personal care and pharmaceutical products. VEEGUM HV is a highly purified smectite clay suspension stabilizer, emulsion optimizer and rheology modifier. VEEGUM HV also reduces the slippery or sticky feel of gums and polymers, while providing a silky, tack-free feel in topical preparations. This smectite clay is synergistic with common thickeners such as VANZAN® xanthan gum and CMC. These combinations will provide greater thickening, stabilizing and suspending properties than those developed by the individual components of the mixture. Typical Use Levels: Between 0.5% and 3% INCI Name: Magnesium Aluminum Silicate VEEGUM HV is Magnesium Aluminum Silicate NF Type IC

VEEGUM® Ultra Magnesium Aluminum Silicate is a unique acidic smectite clay that produces dispersions in the 4.2-5.2 pH range for optimum compatibility with the naturally acidic pH of the skin. VEEGUM Ultra is the easiest of all the grades to hydrate and has a unique white color. VEEGUM Ultra is for use in any low pH formulation and is particularly useful in sunscreens, acne treatments, and exfoliants. VEEGUM Ultra is a highly purified smectite clay suspension stabilizer, emulsion optimizer and rheology modifier. VEEGUM Ultra also reduces the slippery or sticky feel of gums and polymers, while providing a silky, tack-free feel in topical preparations. This smectite clay is synergistic with common thickeners such as VANZAN® xanthan gum and CMC. These combinations will provide greater thickening, stabilizing and suspending properties than those developed by the individual components of the mixture.

VANATURAL® Bentonite Clay is a rapidly hydrating, water-washed bentonite clay. VANATURAL is a pure and natural suspension stabilizer, emulsion optimizer and rheology modifier for all topical products marketed as organic or natural. VANATURAL disperses easily into water and hydrates rapidly. VANATURAL also reduces the slippery or sticky feel of gums and polymers, while providing a silky, tack-free feel in topical preparations. This bentonite clay is synergistic with common thickeners such as VANZAN® xanthan gum and CMC. These combinations will provide greater thickening, stabilizing and suspending properties than those developed by the individual components of the mixture. VANATURAL is OMRI-listed and authorized by ECOCERT Greenlife as complying with the ECOCERT and COSMOS standards for ecological and organic skin care products and cosmetics.

CEAMPHARMA® is a plant based alternative to gelatin used as gelling, texturizing, heat resistance or viscosity agent in a wide range of nutraceutical applications. In syrup applications, it is used as a suspension and viscosity agent in liquid pharmaceutical formats.

VEEGUM® Pure Magnesium Aluminum Silicate is a general-purpose grade that complies with the standards for ecological and organic cosmetics. VEEGUM Pure is a highly purified smectite clay suspension stabilizer, emulsion optimizer and rheology modifier. VEEGUM Pure also reduces the slippery or sticky feel of gums and polymers, while providing a silky, tack-free feel in topical preparations. This smectite clay is synergistic with common thickeners such as VANZAN® xanthan gum and CMC. These combinations will provide greater thickening, stabilizing and suspending properties than those developed by the individual components of the mixture. VEEGUM Pure is OMRI™-listed and authorized by ECOCERT Greenlife™ as complying with the ECOCERT and COSMOS™ standards for ecological and organic skin care products and cosmetics.

The original and most widely used grade, VEEGUM® R Magnesium Aluminum Silicate is used in a variety of cosmetics and personal care products. VEEGUM R is a highly purified smectite clay suspension stabilizer, emulsion optimizer and rheology modifier. VEEGUM R also reduces the slippery or sticky feel of gums and polymers, while providing a silky, tack-free feel in topical preparations. This smectite clay is synergistic with common thickeners such as VANZAN® xanthan gum and CMC. These combinations will provide greater thickening, stabilizing and suspending properties than those developed by the individual components of the mixture.Typical Use Levels: Between 0.5% and 3%INCI Name: Magnesium Aluminum SilicateVEEGUM R is Magnesium Aluminum Silicate NF Type IA

VANATURAL® XGB Bentonite Clay is a synergistic blend of natural bentonite and xanthan gum that hydrates quickly, even with low shear mixing in unheated water. The combination of bentonite clay and xanthan gum will provide greater thickening, stabilizing and suspending properties than those developed by the individual components of the mixture. VANATURAL XGB imparts a pleasant application feel while reliably stabilizing water-based suspensions and emulsions over a broad range of pH and storage temperatures. VANATURAL XGB is recommended for difficult to stabilize suspensions and emulsions. VANATURAL XGB is authorized by ECOCERT Greenlife™ as complying with the ECOCERT and COSMOS™ standards for ecological and organic skin care products and cosmetics.

VEEGUM® D Magnesium Aluminum Silicate is a dental care grade that ensures a stable and short paste or gel with excellent brush stand-up, flavor release and rinse ability. VEEGUM D works synergistically with organic gum binders, allowing the fine-tuning of dentifrice properties with minimal inhibition of fluoride recovery. VEEGUM D also reduces the slippery, stringy or sticky feel of gums and polymers. The incorporation of soluble pyrophosphate with VEEGUM D maximizes fluoride bioavailability.

VEEGUM® HS Magnesium Aluminum Silicate provides maximum electrolyte stability and minimum acid demand. It is used pharmaceutical suspensions, hair care formulas containing conditioning agents, and facemasks. Its relatively low viscosity contribution allows it to be used at levels high enough to enhance skin cleansing. VEEGUM HS is a highly purified smectite clay suspension stabilizer, emulsion optimizer and rheology modifier. VEEGUM HS also reduces the slippery or sticky feel of gums and polymers, while providing a silky, tack-free feel in topical preparations. This smectite clay is synergistic with common thickeners such as VANZAN® xanthan gum and CMC. These combinations will provide greater thickening, stabilizing and suspending properties than those developed by the individual components of the mixture.

Microcare™ 350GMP is a ultrafine #1 prime yellow carnauba wax for use as a coating and binding excipient in pharmaceutical and nutraceutical products.

VEEGUM® K Magnesium Aluminum Silicate Provides good suspension at low viscosity while having low acid demand and high electrolyte and acid compatibility. This grade is well suited for acidic pH pharmaceutical suspensions and hair care formulas containing conditioning agents.VEEGUM K is a highly purified smectite clay suspension stabilizer, emulsion optimizer and rheology modifier. VEEGUM K also reduces the slippery or sticky feel of gums and polymers, while providing a silky, tack-free feel in topical preparations. This smectite clay is synergistic with common thickeners such as VANZAN® xanthan gum and CMC. These combinations will provide greater thickening, stabilizing and suspending properties than those developed by the individual components of the mixture.

Glycerin IP also known as glycerol, is a colorless, odorless, transparent viscous liquid commonly utilized in pharmaceuticals. It is widely used for its excellent moisturizing and humectant properties, playing a key role in various formulations to ensure moisture retention and stability.

Glycerin USP is a liquid-grade glycerin primarily used in pharmaceutical applications. It serves as a binder, carrier, humectant, and plasticizer, making it essential in drug delivery systems, especially for oral solutions. As an excipient, it is used in formulations requiring moisture retention and flexibility, and it is commonly utilized in the production of oral care solutions and processing aids for pharmaceutical products.

Tylopur ClearCoat Nutra® provides a multifunctional coating that not only provides brilliant, transparent and shiny finish to your nutraceutical tablets but additionally protects them against humidity and friability. Moreover, coating with Tylopur ClearCoat Nutra® improves tablets’ swallowability.

TYLOPUR Xtend Nutra® is a plant derived ingredient (high viscous hydroxypropyl methylcellulose, HPMC) that has been developed by Shin-Etsu to provide a controlled, extended release of active compounds over a longer period of time, prolonging their effects on human body. TYLOPUR Xtend Nutra® acts as a hydrophilic matrix agent in hydrophilic matrix system, which is the simplest sustained release technology, consisting essentially of an active compound and a water soluble highly viscous natural polymer. Such a system allows a simple and straight forward direct compression formulation and a reduction of doses per day. It is not only cost effective but it is also consumer friendly. The mechanism of action of TYLOPUR Xtend Nutra® in hydrophilic matrix tablets consists of initial swelling caused by the hydration of a tablet, protective gel formation, which regulates the degree of active compound’s release, and time-related extended release of an active compound through the gel layer.

TYLOPUR Xtend Nutra® is a plant derived ingredient (high viscous hydroxypropyl methylcellulose, HPMC) that has been developed by Shin-Etsu to provide a controlled, extended release of active compounds over a longer period of time, prolonging their effects on human body. TYLOPUR Xtend Nutra® acts as a hydrophilic matrix agent in hydrophilic matrix system, which is the simplest sustained release technology, consisting essentially of an active compound and a water soluble highly viscous natural polymer. Such a system allows a simple and straight forward direct compression formulation and a reduction of doses per day. It is not only cost effective but it is also consumer friendly. The mechanism of action of TYLOPUR Xtend Nutra® in hydrophilic matrix tablets consists of initial swelling caused by the hydration of a tablet, protective gel formation, which regulates the degree of active compound’s release, and time-related extended release of an active compound through the gel layer.

Tylopur ClearCoat Nutra® provides a multifunctional coating that not only provides brilliant, transparent and shiny finish to your nutraceutical tablets but additionally protects them against humidity and friability. Moreover, coating with Tylopur ClearCoat Nutra® improves tablets’ swallowability.

METOLOSE® SM 4000 consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) each available in several grades differing in viscosity.

Capsules prepared from hypromellose have advantages in comparison with gelatin based capsules. Hypromellose capsules show a better moisture stability and are suitable for vegetarian/vegan patients. Low viscosity hypromellose products like METOLOSE 65SH-5 is suitable for capsule manufacturing.

METOLOSE® SM 25 consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) each available in several grades differing in viscosity.

METOLOSE® consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) . METOLOSE SB-4 is an excellent sugar coating binder for solid dosage forms.

METOLOSE® SM 100 consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) each available in several grades differing in viscosity.