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CAVAMAX® W8 Pharma

1 of 12 products in this brand
CAVAMAX® W8 Pharma is pharmaceutical-grade gamma-cyclodextrin from Wacker Chemie AG. This product, with 8 glucose units, has the largest cavity of the parent cyclodextrins and is the most water-soluble. It is useful for solubilizing, stabilizing, or delivering larger molecules, such as macrocyclics, oils, lipids, etc.

INCI Name: Gamma Cyclodextrin

Chemical Name: Gamma Cyclodextrin

CAS Number: 17465-86-0

Functions: Carrier, Solubilizer, Solubilizer, Stabilizer, Stabilizer, Taste Masker

Synonyms: Cyclooctaamylose, Cyclooctapentylose, gamma-CD, gamma-Cyclodextrin, Sodium Gamma-Cyclodextrin Phosphate

Technical Data Sheet

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Knowde Enhanced TDS

Identification & Functionality

Chemical Family

Cyclodextrins

Chemical Name

Gamma Cyclodextrin

INCI Name

Gamma Cyclodextrin

Cosmetic Ingredients Functions

Carrier,

Solubilizer,

Stabilizer

Pharma & Nutraceuticals Functions

Solubilizer,

Stabilizer,

Taste Masker

CAS No.
17465-86-0
Molecular formula
C₄₈H₈₀O₄₀
EC No.
241-482-4
Technologies

Cosmetic Ingredients,

Pharmaceuticals & Nutraceuticals

Product Families

Pharmaceuticals & Nutraceuticals — Excipients

Emulsifiers & Stabilizers,

Flavors & Taste Maskers,

Solvents & Solubilizers

Cosmetic Ingredients — Functionals

Emulsifiers, Solubilizers & Dispersants,

Solvents & Carriers,

Stabilizers

Chemical Structure

CAVAMAX® W8 Pharma - Chemical Structure

Features & Benefits

Benefit Claims

Improves Bioavailability,

Solubilizing,

Stabilizing

Labeling Claims

Cruelty-Free,

Halal,

Kosher

Applications & Uses

Markets

Healthcare & Pharma

Applications

Healthcare & Pharma — Drug Delivery & Care Solutions

Oral

Application Details

Solubilization, stabilization and delivery of large active ingredients, e.g. steroids, lipids
Enhancement of both oral bioavailability and taste masking of pharmaceutical active ingredients; enabling of delayed release.

Applications
  • CAVAMAX® Cyclodextrins & CAVASOL® Cyclodextrin Derivatives
  • Personal Care
  • Pharma

Properties

Physical Form

Powder,

Solid

Typical Properties
ValueUnitsTest Method / Conditions
Molecular Weight1297g/mol—
Bulk Density400 - 700 kg/m³—
Solubility in Water (at 20°C)180.1g/lOECD 105
Microbiological Values
ValueUnitsTest Method / Conditions
Escherichia coli0per 10gMicrobiological photometric test
Microorganismsmax. 1000 per gramMicrobiological photometric test
Molds and Yeastsmax. 100per gramMicrobiological photometric test
Salmonella0per 10gMicrobiological photometric test
Specifications
ValueUnitsTest Method / Conditions
Absorbance (10% solution, at 420nm)max. 0.2—USP/NF
Cyclodextrin Content98.0 - 102.0%HPLC Method
Heavy Metalsmax. 5 ppmUSP/NF
Loss on Dryingmax. 11.0 %Halogen dryer
Reducing Substancesmax. 0.2%PH. EUR.
Related Substancesmax. 0.5%USP/NF
Related Substances (sum)max. 0.5%USP/NF
Residue on Ignitionmax. 0.1 %USP/NF
Specific Rotation ([α]/D20)174.0 - 180.0 DegreeUSP/NF
Volatile Organic Compoundsmax. 50ppmGas Chromatography
Properties
  • DMF Type IV, No 11375
  • White powder
  • Pharmaceutical grade: Content min. 98.0%, complies with current USP/NF monographs specifications.

Regulatory & Compliance

Certifications & Compliance

Cruelty-Free,

EPA Registered,

FSSC 22000,

Halal,

Kosher,

National Formulary (NF),

REACH (Europe),

United States Pharmacopeia (USP)

Chemical Inventories

TSCA (USA)

Grade

Pharma Grade

Packaging & Availability

Country Availability

Afghanistan,

Albania,

Algeria,

American Samoa,

Andorra,

Angola,

Anguilla,

Antigua And Barbuda,

Argentina,

Armenia,

Aruba,

Australia,

Austria,

Azerbaijan,

Bahamas,

Bahrain,

Bangladesh,

Barbados,

Belarus,

Belgium,

Belize,

Benin,

Bermuda,

Bhutan,

Bolivia,

Bosnia and Herzegovina,

Botswana,

Bouvet Island,

Brazil,

British Indian Ocean Territory,

Brunei Darussalam,

Bulgaria,

Burkina Faso,

Burundi,

Cambodia,

Cameroon,

Canada,

Cape Verde,

Cayman Islands,

Central African Republic,

Chad,

Chile,

China (Mainland),

Christmas Island,

Cocos Islands,

Colombia,

Comoros,

Congo,

Cook Islands,

Costa Rica,

Cote D'Ivoire,

Croatia,

Cuba,

Cyprus,

Czech Republic,

Denmark,

Djibouti,

Dominica,

Dominican Republic,

Ecuador,

Egypt,

El Salvador,

Equatorial Guinea,

Eritrea,

Estonia,

Ethiopia,

Falkland Islands,

Faroe Islands,

Fiji,

Finland,

France,

French Guiana,

French Polynesia,

Gabon,

Gambia,

Georgia,

Germany,

Ghana,

Gibraltar,

Greece,

Greenland,

Grenada,

Guadeloupe,

Guam,

Guatemala,

Guinea,

Guinea-Bissau,

Guyana,

Haiti,

Heard Island and McDonald Islands,

Honduras,

Hong Kong,

Hungary,

Iceland,

India,

Indonesia,

Iran,

Iraq,

Ireland,

Israel,

Italy,

Jamaica,

Japan,

Jordan,

Kazakhstan,

Kenya,

Kiribati,

Korea,

Kuwait,

Kyrgyzstan,

Laos,

Latvia,

Lebanon,

Lesotho,

Liberia,

Libyan Arab Jamahiriya,

Liechtenstein,

Lithuania,

Luxembourg,

Macao,

Macedonia,

Madagascar,

Malawi,

Malaysia,

Maldives,

Mali,

Malta,

Marshall Islands,

Martinique,

Mauritania,

Mauritius,

Mayotte,

Mexico,

Micronesia,

Moldova,

Monaco,

Mongolia,

Montenegro,

Montserrat,

Morocco,

Mozambique,

Myanmar,

Namibia,

Nauru,

Nepal,

Netherlands,

Netherlands Antilles,

New Caledonia,

New Zealand,

Nicaragua,

Niger,

Nigeria,

Niue,

Norfolk Island,

North Corea,

Northern Mariana Islands,

Norway,

Oman,

Pakistan,

Palau,

Palestinian Territory,

Panama,

Papua New Guinea,

Paraguay,

Peru,

Philippines,

Pitcairn,

Poland,

Portugal,

Puerto Rico,

Qatar,

Reunion,

Romania,

Russia,

Rwanda,

Saint Helena,

Saint Kitts and Nevis,

Saint Lucia,

Saint Pierre And Miquelon,

Saint Vincent And The Grenadines,

Samoa,

San Marino,

Sao Tome and Principe,

Saudi Arabia,

Senegal,

Serbia,

Seychelles,

Sierra Leone,

Singapore,

Slovakia,

Slovenia,

Solomon Islands,

Somalia,

South Africa,

Spain,

Sri Lanka,

Sudan,

Suriname,

Svalbard And Jan Mayen,

Swaziland,

Sweden,

Switzerland,

Syrian Arab Republic,

Taiwan,

Tajikistan,

Tanzania,

Thailand,

Togo,

Tokelau,

Tonga,

Trinidad And Tobago,

Tunisia,

Turkey,

Turkmenistan,

Turks And Caicos Islands,

Tuvalu,

USA,

Uganda,

Ukraine,

United Arab Emirates,

United Kingdom,

United States Minor Outlying Islands,

Uruguay,

Uzbekistan,

Vanuatu,

Vatican City,

Venezuela,

Vietnam,

Virgin Islands, British,

Virgin Islands, U.S.,

Wallis And Futuna,

Western Sahara,

Yemen,

Zambia,

Zimbabwe

Regional Availability
  • Africa
  • Asia
  • Europe
  • Latin America
  • Middle East
  • North America
  • Oceania
Packaging Information

Units of 20 kg

Storage & Handling

Storage Information

Storage at room temperature in sealed containers under dry conditions is recommended. CAVAMAX® W8 PHARMA has a shelf life of at least 36 months when stored inunbroken original packaging in dry storage areas.