Knowde Enhanced TDS
Identification & Functionality
- Chemical Name
- Pharma & Nutraceuticals Functions
- CAS No.
- 112945-52-5
- EC No.
- 601-216-3
- Technologies
Features & Benefits
- Labeling Claims
Applications & Uses
- Markets
- Dosage Form
- Applications
- Pharma
- Rheology Control & Free-Flow Agent
- Application Details
- HDK® N20 P PHARMA is intended for use in pharmaceuticals. It improves the flow of powders and is used as glidant for tableting.
- A good mixing and dispersion of HDK® N20 P PHARMA is a must to assure optimum performance.
Properties
- Appearance
- White colloidal powder
- Typical Properties
- Specifications
- Properties
White colloidal powder of high purity.
| Value | Units | Test Method / Conditions | |
| Density (at 20°C, SiO₂) | approx. 2.2 | g/cm³ | DIN 51757 |
| Loss of Weight (at 1000°C, 2hours (based on the substance dried at 105 °C for 2 hours)) | max. 2 | % | DIN EN ISO 3262-19 |
| Refraction Index | 1.46 | — | — |
| Silanol Group Density | 2 | SiOH/nm² | — |
| SiO₂ Content (based on the substance heated at 1000°C for 2hours) | min. 99.8 | % | DIN EN ISO 3262-19 |
| Value | Units | Test Method / Conditions | |
| Arsennic Content (As) | max. 3 | ppm | USP/AAS |
| BET Surface | 175 - 225 | m²/g | DIN ISO 9277 DIN 66132 |
| Chloride Content (Cl) | max. 250 | ppm | Ph. Eur. |
| Loss on Drying | max. 1.5 | % | USP |
| Loss on Ignition | max. 2 | % | USP |
| pH (at 40 g/l) | 3.8 - 4.3 | — | DIN EN ISO 787-9 |
| Sieve Residue (min. 40 µm) | max. 0.03 | % | DIN EN ISO 787-18, Mocker Apparatus |
| Silicone Dioxide Content | min. (99.0 - 100.5) | % | USP |
| Tamped Density | approx. 100 | g/l | DIN EN ISO 787-11 |
Regulatory & Compliance
- Certifications & Compliance
- Grade
- Quality Standards
- Complaince
HDK® N20 P PHARMA is tested according to the pharmacopeias EP and USP/NF. (Produced according to ISO 9001, ISO 14001, HACCP and IPEC).
Safety & Health
- Safety Notes
During transportation and processing HDK® N20 P PHARMA may cause electrostatic charges. Like other amorphous silicas HDK® N20 P PHARMA does not show either carcinogenic (IARC classification, Volume 68, 1997) or mutagenic properties.
Packaging & Availability
- Country Availability
- Packaging Type
- Regional Availability
- Packaging Information
Pallet with paper bags: 20 kg bags.
Storage & Handling
- Storage Information
HDK® N20 P PHARMA should be stored in the original packaging in dry storage areas. Due to the high surface area HDK® adsorbs volatiles and should be protected from humidity and volatiles. If single bags are taken away from an original pallet, the remaining bags of this pallet must again be protected against humidity and volatiles.